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PUM1

Anti-PUM1 Products

Recombinant Rabbit Anti-PUM1 Monoclonal Antibody (JG37-75) (MRO-1299-CN)
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC, IP
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Rabbit Anti-PUM1 Recombinant Antibody (clone JG37-75) (VS3-WK472)
- Derivation: Rabbit
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, ELISA
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Recombinant Rabbit Anti-PUM1 Antibody (clone R04-3A6) (VS3-FY1228)
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, ICC, IF, IP
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Anti-PUM1 Immunohistochemistry Kit (VS-0325-XY1831)
- Species Reactivity: Human, Mouse, Rat
- Target: PUM1
- Application: IHC
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Hi-Affi™ Recombinant Rabbit Anti-PUM1 Monoclonal Antibody (DS2941AB) (MOR-2941)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: FC, ICC/IF, IHC-P, IP, WB
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For Research Use Only. Not For Clinical Use.

Background

This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans.

Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Recruits the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation (PubMed:22955276). In case of viral infection, interacts with DHX58 (PubMed:25340845). Interacts with TRIM71 (via NHL repeats) in an RNA-dependent manner (PubMed:23125361).

Molecular function

RNA-binding

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