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RDH12
Loading...Anti-RDH12 Products
- Mouse Anti-RDH12 Recombinant Antibody (clone 1E11) (VS-0625-FY69)
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- Species Reactivity: Human
- Type: Mouse IgG2a, kappa
- Application: WB, ELISA, ICC, IF
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 13 and Retinitis Pigmentosa 53.
