+ Filter
Loading...
Custom Services order now ship next day

Anti-S1PR3 Recombinant Antibody Products

Loading...

Anti-S1PR3 Products

View More Products

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


Given its significant role in regulating immune responses, S1PR3 presents a promising therapeutic target for immune-related disorders. Creative Biolabs offers a diverse collection of recombinant anti-S1PR3 antibodies, expertly engineered using our advanced technology to ensure high specificity and reactivity, thereby accelerating the development of novel therapeutic strategies.

S1PR3: A Promising Target for Cancer Immunotherapy

S1P's interaction with S1PR3 primarily drives tumor development through activation of PI3K, MAPK, and PLC pathways. Interestingly, S1PR3 appears to dampen the immune response by encouraging tumor blood vessel formation and shifting macrophages to an immunosuppressive state. Furthermore, S1P-S1PR3 signaling might contribute to a tumor-promoting inflammatory milieu by influencing cytokine release within the tumor microenvironment. Despite these complexities, the multifaceted role of S1PR3 makes it a compelling focus for the design of novel cancer immunotherapies.

Alternative Names

Sphingosine-1-phosphate receptor 3; S1P receptor 3; S1PR3; EDG-3; EDG3; LPB3; S1P3.

Background

This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.

Protein class

FDA approved drug targets, G-protein coupled receptors

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Theca cells, Sertoli cells, Endometrial stromal cells, Smooth muscle cells)

Immune cell specificity

Immune cell enriched (classical monocyte)

Cell line specificity

Cell line enhanced (AF22, ASC diff, ASC TERT1)

Molecular function

G-protein coupled receptor, Receptor, Transducer [Q99500]

More Types Infomation

Anti-S1PR3 rAb Products

Creative Biolabs provides high-quality recombinant anti-S1PR3 antibodies developed using cutting-edge technology, assuring consistency and specificity for study. These valuable tools allow scientists to thoroughly investigate S1PR3's expression, function, and signaling in various models. By targeting S1PR3, these antibodies help researchers understand its role in processes like immune cell movement and blood vessel function, thus improving our understanding of this receptor in different diseases.

Table 1. Featured anti-S1PR3 recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
HPAB-0437-WJ Mouse Anti-S1PR3 Recombinant Antibody (clone 7H9F11) Human Mouse IgG ELISA, ICC
HPAB-0437-WJ-F(E) Mouse Anti-S1PR3 Recombinant Antibody (clone 7H9F11); Fab Fragment Human Mouse Fab ELISA, ICC
HPAB-0437-WJ-S(P) Mouse Anti-S1PR3 Recombinant Antibody (clone 7H9F11); scFv Fragment Human Mouse scFv ELISA, ICC
MOB-1777MZ Recombinant Mouse Anti-Human S1PR3 Antibody (clone BT72) Human Mouse antibody WB
VS-0624-FY30 Human Anti-S1PR3 Recombinant Antibody (clone AS55) Human Human IgG ELISA

Creative Quality Control

Creative Biolabs ensures the high quality of the anti-S1PR3 recombinant antibodies through rigorous quality control. Each batch undergoes thorough testing, including SDS-PAGE, WB, ELISA, and other assays, to confirm consistent purity, specific binding to the S1PR3 target, and minimal off-target interactions. This comprehensive validation process provides researchers with dependable and reproducible antibodies, crucial for reliable S1PR3 signaling research.

Customer Reviews

Excellent
Ji***g
Recombinant Anti-S1PR3 Vesicular Antibody, EV Displayed (VS-0425-YC566) (CAT#: VS-0425-YC566)
We've been using Creative Biolabs' anti-S1PR3 recombinant antibody in our flow cytometry experiments to identify and characterize specific immune cell populations for months. A brilliant stain with little background is regularly produced by the antibody, which is crucial for quantitative analysis. Batch-to-batch consistency has been excellent, saving us time in optimization. The datasheet was comprehensive and recommended.
11/Mar/2023
Excellent
Mu***i
Recombinant Mouse Anti-Human S1PR3 Antibody (clone BT72) (CAT#: MOB-1777MZ)
We had a great experience with Creative Biolabs from inquiry to antibody delivery. Online ordering was easy, and the antibodies came quickly and well-packaged. Our staining studies were straightforward to carry out due to the clear technique. With a small storage issue, their technical support staff replied immediately and helped. The staining was consistent across tissue slices. This antibody functions well and has great customer service, making it fun to use.
20/Nov/2023
Excellent
Lo***a
Mouse Anti-S1PR3 Recombinant Antibody (clone 7H9F11); Fab Fragment (CAT#: HPAB-0437-WJ-F(E))
The high purity of Creative Biolabs' recombinant anti-S1PR3 antibody is evident in our immunocytochemistry experiments. We've achieved clear and specific labeling of S1PR3 on various cell types, with low background noise. The accompanying technical data sheet was comprehensive and provided helpful guidance for optimizing our staining protocols. Overall, this antibody has proven to be a robust and dependable tool for our studies on S1PR3 expression.
13/Jun/2024

rAb Production

Unlock the potential of your S1PR3 research with Creative Biolabs' premium recombinant antibodies. Engineered with cutting-edge technology and rigorously validated, our antibodies provide a consistent and high-quality foundation for exploring the complexities of S1PR3 signaling and driving scientific discovery.

Featured Anti-xx Recombinant Antibody Production PlatformsFig.1 Milligram-scale. (Creative Biolabs Original)
Fig.1 Milligram-scale anti-S1PR3 recombinant antibody production.

Fig.2 Gram-scale. (Creative Biolabs Original)Fig.2 Gram-scale anti-S1PR3 recombinant antibody production.

rAb Modalities

Researchers globally rely on Creative Biolabs for exceptional, custom-designed recombinant anti-S1PR3 antibodies, meticulously crafted to address their unique experimental requirements.

Fig.3 S1PR3 antibody production and modalities. (Creative Biolabs Original)Fig.3 Full-length anti-S1PR3 recombinant antibody production and modalities.

S1PR-Targeted Drug Information-1

Table 2. Public drug targeting S1PR.

Company Research phase Classification Condition
ALS Therapy Development Inst (ALS TDI) (ALS Therapy Development Institute)
ALS Therapy Development Institute
First Affiliated Hosp Fujian Med Univ
Indiana University
Mitsubishi Tanabe Pharma (Originator)
Novartis
Taito (Originator)
Launched - 2010 Prodrugs Amyotrophic lateral sclerosis
Asthma
Chronic inflammatory demyelinating polyneuropathy
Immunosuppression
Multiple sclerosis
Multiple sclerosis, primary progressive
Multiple sclerosis, relapsing-remitting
Optic neuritis
Polyneuropathy, demyelinating
Renal Disorders
Rett syndrome
Schizophrenia
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19)
Transplant rejection
Transplant rejection, kidney
Lpath (Originator)
Lpath Therapeutics (Lpath)
Merck Serono
Pfizer
Phase II Cancer Immunotherapy
Humanized Monoclonal Antibodies
Cancer
Cancer, kidney (renal cell carcinoma)
Heart failure
Retinal detachment
Wet macular degeneration (exudative)
VYNE Therapeutics (Originator) Phase I/II Fixed-Dose Combinations
Prodrugs
Atopic dermatitis
Institute of Materia Medica of Beijing (Originator) Phase I Prodrugs Psoriasis
Washington University (Originator) Phase I Carbon-Radiolabeled Products
Nuclear Imaging Agents
Atherosclerosis
Injury, vascular
Multiple sclerosis
Neurodegeneration
Neuroinflammation
Bristol-Myers Squibb (Originator) Phase I Prodrugs Autoimmune disease
Rheumatoid arthritis
Daiichi Sankyo (Originator) Discontinued Prodrugs Immunological Disorders
Multiple sclerosis
Washington University (Originator) Preclinical Fluorine-Radiolabeled Products
Nuclear Imaging Agents
Neuroinflammation
Capital Medical University (CMU) (Originator)
Ocean University of China (Originator)
Preclinical Chemosensitizers Cancer, colorectal
Washington University (Originator) Preclinical Fluorine-Radiolabeled Products
Nuclear Imaging Agents
Neurological Disorders
Washington University (Originator) Preclinical Fluorine-Radiolabeled Products
Nuclear Imaging Agents
Neurological Disorders

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

S1PR-Targeted Drug Information-2

Table 3. Drug targeting S1PR (under development).

Company Research phase Classification Condition
Autobahn Therapeutics (Originator) Biological Testing Prodrugs Adrenoleukodystrophy, X-linked
Multiple sclerosis
Autobahn Therapeutics (Originator) Biological Testing Prodrugs Adrenoleukodystrophy, X-linked
Multiple sclerosis
Novartis (Originator) Biological Testing Deuterated Compounds Inflammation, lung
Korea Institute of Science & Technology (Originator) Biological Testing Selenium Compounds Multiple sclerosis
Korea Institute of Science & Technology (Originator) Biological Testing Prodrugs
Selenium Compounds
Multiple sclerosis
Korea Institute of Science & Technology (Originator) Biological Testing Selenium Compounds Multiple sclerosis
Beijing Shenlantai Pharmaceutical Technology (Originator) Biological Testing Chemosensitizers Cancer
University of California (Originator) Biological Testing Pegylated Drugs
Prodrugs
Cancer
Multiple sclerosis
Celgene Biological Testing Cocrystals Multiple sclerosis
Psoriasis

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

With a strong foundation in antibody engineering and manufacturing, Creative Biolabs delivers high-quality S1PR3 recombinant antibodies, designed for consistent and exceptional performance across various research applications. Understanding the critical importance of S1PR3 in your investigations, we are dedicated to providing antibodies that adhere to the highest standards of reliability. Researchers delving into the complexities of S1PR3 are invited to contact us for customized pricing that suits their unique research requirements.

Go to compare

Go to compare