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SAA1
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- PE-A*02:01/Human SAA1 (YTCPLCRAPV) MHC Tetramer (MHC-CN1193)
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- Class: Class I
- Antigen: SAA1
- Antigen Species: Human
- Peptide: YTCPLCRAPV
- Conjugate: PE
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- Recombinant Mouse Anti-SAA1 Antibody (VS-0923-FY135) (VS-0923-FY135)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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- APC-A*02:01/Human SAA1 (YTCPLCRAPV) MHC Tetramer (MHC-CN1194)
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- Class: Class I
- Antigen: SAA1
- Antigen Species: Human
- Peptide: YTCPLCRAPV
- Conjugate: APC
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- FITC-A*02:01/Human SAA1 (YTCPLCRAPV) MHC Tetramer (MHC-CN1195)
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- Class: Class I
- Antigen: SAA1
- Antigen Species: Human
- Peptide: YTCPLCRAPV
- Conjugate: FITC
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- A*02:01/Human SAA1 (YTCPLCRAPV) MHC Tetramer (MHC-CN1196)
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- Class: Class I
- Antigen: SAA1
- Antigen Species: Human
- Peptide: YTCPLCRAPV
- Conjugate: Unconjugated
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- Mouse Anti-SAA1 Recombinant Antibody (CBS105D) (MOB-0811-YJ)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: IHC-Fr, IA, IHC-P, WB
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- Mouse Anti-SAA1 Recombinant Antibody (CBS106D) (MOB-0812-YJ)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: IHC-Fr, IA, IHC-P, WB
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- Human Anti-SAA1 Recombinant Antibody; scFv Fragment (HPAB-0045-FY-S(P)) (HPAB-0045-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: Cyt
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- Human Anti-SAA1 Recombinant Antibody; Fab Fragment (HPAB-0045-FY-F(E)) (HPAB-0045-FY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: Cyt
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC-P
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- Rabbit Anti-SAA1 Recombinant Antibody (VS13-YC1033) (VS13-YC1033)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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- Human Anti-SAA1 scFv-Fc Chimera (VS-0425-FY181) (VS-0425-FY181)
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- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: WB, ELISA, IHC
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- Mouse Anti-SAA1 Recombinant Antibody (clone 1A12E5) (VS7-0425-WR816)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC, FC
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- Mouse Anti-SAA1 Recombinant Antibody (clone 6A5B10) (VS7-0425-WR817)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA
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- Anti-SAA1 Immunohistochemistry Kit (VS-0525-XY6330)
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- Species Reactivity: Human
- Target: SAA1
- Application: IHC
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- Anti-Mouse SAA1 Immunohistochemistry Kit (VS-0525-XY6331)
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- Species Reactivity: Human, Mouse
- Target: SAA1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Feb 2016]
Protein class
Disease related genes
Predicted location
Secreted
Single cell type specificity
Cell type enriched (Hepatocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (HBEC3-KT)
Interaction
Homohexamer; dimer of trimers. Can form amyloid fibrils after partial proteolysis; the native, undenatured protein does not form amyloid fibrils (in vitro). Apolipoprotein of the HDL complex. Binds to heparin.
Molecular function
Heparin-binding
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