Anti-SAA1 (clone W24V151) Recombinant Antibody Coupled Liposome (VS-1024-FY151)
CAT#: VS-1024-FY151
Anti-SAA1 antibody-conjugated liposomes represent a promising strategy for the targeted delivery of therapeutic agents in the treatment of colorectal cancer, specifically by zeroing in on the SAA1 protein expressed in tumor tissues. This targeted approach not only increases the local concentration of the drug within the tumor environment, thereby potentially enhancing the overall treatment efficacy, but it may also lead to significant changes in the immune landscape of the tumor. By modulating the immune response, this innovative delivery system could pave the way for more effective combination therapies that leverage the body's immune system to combat cancer.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enriched (HBEC3-KT)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000173432-SAA1
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More Infomation
Specifications
- Potential Clinical Applications
- Colorectal cancer
Product Composition
- Clone
- W24V151
- Antibody Type
- IgG
- Antibody Host
- Human
- Antibody Reactivity
- Human
- Antibody Description
- This is a recombinant human monoclonal antibody specifically engineered to target Serum Amyloid A protein (SAA1). This antibody has been meticulously developed using advanced biotechnological methods to ensure high specificity and affinity for the SAA1 protein, which is known to play a significant role in inflammatory responses and various diseases, including amyloidosis.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- SAA1
- Introduction
- This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.
- Alternative Names
- Serum Amyloid A1; SAA; Tumor Protein P53 Inducible Protein 4; Serum Amyloid A-1 Protein; Serum Amyloid A Protein; TP53I4; PIG4; SAA2
- Full Name
- Serum Amyloid A1
- Gene ID
- 6288
- UniProt ID
- P0DJI8
- Sequence Similarities
- Belongs to the SAA family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end. ( P0DJI8-SAA1_HUMAN )
Modification sites at PhosphoSitePlus ( P0DJI8 )
Modification sites at neXtProt
- Protein Refseq
- NP_000322.3; NP_001171477.2; NP_954630.2
- Function
- Major acute phase protein.
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Datasheet
MSDS
COA
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See other products for "SAA1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0034MZ | Recombinant Mouse Anti-Human SAA1 Antibody (clone C333A) | ELISA, WB | Mouse antibody |
| ZG-0207U | Mouse Anti-SAA1 Recombinant Antibody (clone 1F2E1) | ELISA | Mouse IgG2b |
| VS3-WK692 | Mouse Anti-SAA1 Recombinant Antibody (clone K11h8) | WB, ELISA | Mouse IgG |
| VS3-WK726 | Mouse Anti-SAA1 Recombinant Antibody (clone K7c5) | WB, ELISA | Mouse IgG |
| VS3-WK731 | Mouse Anti-SAA1 Recombinant Antibody (clone K8d6) | WB, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3164 | Hi-Affi™ Recombinant Rabbit Anti-SAA1 Monoclonal Antibody (DS3164AB) | WB, IHC-P | IgG |
| MOR-4733 | Hi-Affi™ Recombinant Rabbit Anti-SAA1 Monoclonal Antibody (TH247DS) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0045-FY-S(P) | Human Anti-SAA1 Recombinant Antibody; scFv Fragment (HPAB-0045-FY-S(P)) | Cyt | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0045-FY-F(E) | Human Anti-SAA1 Recombinant Antibody; Fab Fragment (HPAB-0045-FY-F(E)) | Cyt | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1193 | PE-A*02:01/Human SAA1 (YTCPLCRAPV) MHC Tetramer | FCM, IHC | |
| MHC-CN1194 | APC-A*02:01/Human SAA1 (YTCPLCRAPV) MHC Tetramer | FCM, IHC | |
| MHC-CN1195 | FITC-A*02:01/Human SAA1 (YTCPLCRAPV) MHC Tetramer | FCM, IHC | |
| MHC-CN1196 | A*02:01/Human SAA1 (YTCPLCRAPV) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY181 | Human Anti-SAA1 scFv-Fc Chimera (VS-0425-FY181) | WB, ELISA, IHC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6330 | Anti-SAA1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6331 | Anti-Mouse SAA1 Immunohistochemistry Kit | IHC |
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