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SDHB
Anti-SDHB Recombinant Antibody Products
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- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ELISA
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- Rabbit Anti-SDHB Polyclonal Antibody (MRO-2179-CN) (MRO-2179-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
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- Anti-SDHB Immunohistochemistry Kit (VS-0325-XY2017)
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- Species Reactivity: Human, Mouse, Rat
- Target: SDHB
- Application: IHC
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, IP, FC, IHC-P
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- Mouse Anti-SDHB Recombinant Antibody (clone 2E8B11) (VS7-0425-WR837)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC, FC
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- Mouse Anti-SDHB Recombinant Antibody (clone 2B2B1) (VS7-0425-WR836)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC, FC
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For Research Use Only. Not For Clinical Use.
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)
Protein class
Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Transporters
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal tubular cells, Cardiomyocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD (By similarity). Interacts with SDHAF1; the interaction is required for iron-sulfur cluster incorporation into SDHB (PubMed:26749241). (Microbial infection) Interacts with JC virus small t antigen.
Molecular function
Oxidoreductase
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