


SIRT6

Anti-SIRT6 Products
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, FC
- Rabbit Anti-SIRT6 Polyclonal Antibody (MRO-2190-CN) (MRO-2190-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IHC, FC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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- Species Reactivity: Human, Mouse, Rat, Monkey
- Type: Mouse IgG
- Application: WB, ICC
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat, Monkey
- Type: Mouse IgG1
- Application: WB, IF, IP
- Rabbit Anti-SIRT6 Recombinant Antibody (VS3-WK1059) (VS3-WK1059)
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- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, FC
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, ICC, IF, IP
- AbPlus™ Anti-SIRT6 Magnetic Beads (VS-0724-YC437) (VS-0724-YC437)
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- Target: SIRT6
- Target Species: Human
- Application: IP, Protein Purification
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC-P, FC
- Mouse Anti-SIRT6 Recombinant Antibody (clone 2G1E8) (VS7-0425-WR860)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA
- Mouse Anti-SIRT6 Recombinant Antibody (clone 2G1H1) (VS7-0425-WR861)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ICC, FC
- Anti-SIRT6 Immunohistochemistry Kit (VS-0325-XY2072)
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- Species Reactivity: Human, Mouse
- Target: SIRT6
- Application: IHC
- Chicken Anti-SIRT6 Polyclonal IgY (BRD-0793MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
Enzymes, Metabolic proteins
Intracellular
Group enriched (Distal enterocytes, Paneth cells)
Low immune cell specificity
Low cell line specificity
Homodimer; binds to nucleosomes and DNA ends as a homodimer (PubMed:31995034, PubMed:32538779). Interacts with RELA; interferes with RELA binding to target DNA (PubMed:19135889). Interacts with SMARCA5; promoting recruitment of SMARCA5/SNF2H to double-strand breaks (DSBs) sites (PubMed:23911928). Interacts with the mTORC2 complex; preventing the ability of SIRT6 to deacetylate FOXO1. Interacts with the CLOCK-BMAL1 complex; recruited by the CLOCK-BMAL1 complex to regulate expression of clock-controlled genes. Interacts with CSNK2A2; preventing CSNK2A2 localization to the nucleus (By similarity).
Transferase