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    Recombinant Rabbit Anti-SIRT6 Antibody (clone R04-9G5) (CAT#: VS3-FY1341)

    This product is a recombinant rabbit antibody that recognizes SIRT6. This antibody has been reported for use in Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunocytochemistry, Immunofluorescence, Immunoprecipitation. The clone R04-9G5 is specific for human, mouse, rat SIRT6. The antigen is human sirt6 synthetic peptide.

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line MCF7
    Figure 1 IF staining of human cell line MCF7
    (Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/49729/1483_A8_3_selected.jpg
    Figure 2 IF staining of human cell line HaCaT
    Figure 2 IF staining of human cell line HaCaT
    (Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm & vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/71776/1346_C8_2_selected.jpg
    Normal Tissue
    Figure 3 IHC staining of human stomach
    Figure 3 IHC staining of human stomach
    (Immunohistochemical staining of human stomach shows strong nuclear and cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/71776/ihc_selected.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/71776/154204_B_9_5.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/71776/154204_A_9_3.jpg
    Figure 6 Liver
    Figure 6 Liver
    (Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/71776/154204_A_7_4.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/71776/154204_A_8_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Peritubular cells Staining: High Intensity: Strong Quantity: 75%-25% Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: High Intensity: Strong Quantity: 75%-25% Spermatogonia cells Staining: High Intensity: Strong)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/71776/154204_A_6_6.jpg
    Figure 9 Lymph node
    Figure 9 Lymph node
    (Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/71776/154204_A_8_8.jpg
    RNA Expression
    Figure 10 RNA cell line category: Low cell line specificity
    Figure 10 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000077463-SIRT6

    Specifications

    • Immunogen
    • Human SIRT6 Synthetic Peptide.
    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human, Mouse, Rat SIRT6
    • Species Reactivity
    • Human, Mouse, Rat
    • Clone
    • R04-9G5
    • Applications
    • Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
    • Conjugate
    • Unconjugated
    • MW
    • Calculated MW: 39 kDa; Observed MW: 39 kDa

    Product Property

    • Purification
    • Affinity Purified
    • Purity
    • >95% as determined by SDS-PAGE
    • Buffer
    • 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA
    • Preservative
    • 0.01% Sodium azide
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • Western Blot: 1/500-1/1000
      Immunohistochemistry-Paraffin: 1/50-1/100
      Immunofluorescence: 1/50-1/200
      Immunoprecipitation: 1/20

    Target

    • Alternative Names
    • Sirtuin 6; Regulatory Protein SIR2 Homolog 6; SIR2-Like Protein 6; SIR2L6; Sirtuin (Silent Mating Type Information Regulation 2, S. Cerevisiae, Homolog) 6; Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 6 (S. Cerevisiae)

    Recommended Products

    Secondary Antibody

    Isotype Control

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "SIRT6"

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    Chicken IgY Antibody Products Rabbit Monoclonal Antibody Products IgG Antibody Products Antibody Magnetic Beads Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
    CAT Product Name Application Type
    BRD-0793MZ Chicken Anti-SIRT6 Polyclonal IgY WB Chicken antibody

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