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SOX17

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For Research Use Only. Not For Clinical Use.


Background

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Group enriched (Glandular and luminal cells, Adipocytes, Endometrial ciliated cells, Endothelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (EFO-21)

Interaction

Interacts with CTNNB1, LEF1 and TCF4.

Molecular function

Activator, DNA-binding

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