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SPARCL1

SPARC-like protein 1 (SPARCL1), also known as hevin, is a secreted protein with high structural similarity to SPARC. SPARCLl (secreted protein acidic and rich inCysteine like 1) is a member of SPARC family, a glycoprotein exocrine to secretory stromal cells, a tumor suppressor molecule that inhibits cell proliferation, invasion and metastasis. Abnormal changes occur in some tumors, and too little secretion promotes the occurrence and development of tumors.
SPARCL1
Protein class

Cancer-related genes, Plasma proteins

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Sertoli cells, Adipocytes, Smooth muscle cells, Peritubular cells, Skeletal myocytes, Endothelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (AF22, SuSa, U-266/70)

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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