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SPARCL1
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- Chicken Anti-SPARCL1 Polyclonal IgY (BRD-0552MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
SPARC-like protein 1 (SPARCL1), also known as hevin, is a secreted protein with high structural similarity to SPARC. SPARCLl (secreted protein acidic and rich inCysteine like 1) is a member of SPARC family, a glycoprotein exocrine to secretory stromal cells, a tumor suppressor molecule that inhibits cell proliferation, invasion and metastasis. Abnormal changes occur in some tumors, and too little secretion promotes the occurrence and development of tumors.
Protein class
Cancer-related genes, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Sertoli cells, Adipocytes, Smooth muscle cells, Peritubular cells, Skeletal myocytes, Endothelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (AF22, SuSa, U-266/70)
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