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SPINK1
Anti-SPINK1 Recombinant Antibody Products
- Recombinant Mouse Anti-SPINK1 Antibody (CBL662) (NEUT-1978CQ)
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- Species Reactivity: Human
- Type: IgG1
- Application: Neut
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: IHC-P, WB
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- Rabbit Anti-SPINK1 Recombinant Antibody (VS13-YC1106) (VS13-YC1106)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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- Anti-SPINK1 Immunohistochemistry Kit (VS-0325-XY2164)
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- Species Reactivity: Human
- Target: SPINK1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Secreted
Single cell type specificity
Group enriched (Exocrine glandular cells, Pancreatic endocrine cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (CACO-2, RT4)
Molecular function
Protease inhibitor, Serine protease inhibitor
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