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TBXA2R

Anti-TBXA2R Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class

Disease related genes, G-protein coupled receptors, Human disease related genes

Predicted location

Membrane

Single cell type specificity

Group enriched (Hepatic stellate cells, Macrophages, Adipocytes, Endothelial cells)

Immune cell specificity

Immune cell enhanced (naive B-cell)

Cell line specificity

Cell line enhanced (HeLa, U-2197, U-937)

Interaction

Interacts with RPGRIP1L. Interacts with PSMA3. Interacts with RACK1; the interaction regulates TBXA2R cell surface expression.

Molecular function

G-protein coupled receptor, Receptor, Transducer

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