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TBXA2R
This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class
Disease related genes, G-protein coupled receptors, Human disease related genes
Predicted location
Membrane
Single cell type specificity
Group enriched (Hepatic stellate cells, Macrophages, Adipocytes, Endothelial cells)
Immune cell specificity
Immune cell enhanced (naive B-cell)
Cell line specificity
Cell line enhanced (HeLa, U-2197, U-937)
Interaction
Interacts with RPGRIP1L. Interacts with PSMA3. Interacts with RACK1; the interaction regulates TBXA2R cell surface expression.
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
- Recombinant Anti-Human TBXA2R Antibody scFv Fragment (MOB-2443z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: FC, ELISA, FuncS
- Recombinant Anti-Human TBXA2R Antibody Fab Fragment (MOB-2443z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, FACS, FuncS
-
- Species Reactivity: Human
- Type: Mouse IgG3, κ
- Application: WB, IP, IF, ELISA
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.