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TFG

Anti-TFG Products
- Rabbit Anti-TFG Recombinant Antibody (clone CBACN-559) (MRO-1529-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP
- Rabbit Anti-TFG Recombinant Antibody (VS3-WK1084) (VS3-WK1084)
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- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, IP
- Rabbit Anti-TFG Recombinant Antibody (clone R06-8F5) (VS3-FY1915)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, IF
- Anti-TFG Immunohistochemistry Kit (VS-0525-XY7196)
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- Species Reactivity: Human
- Target: TFG
- Application: IHC
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P, FC, ICC, IF
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For Research Use Only. Not For Clinical Use.
Background
There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Self-associates to form an oligomeric complex (PubMed:23479643). Interacts with PDCD6; promoting localization and polymerization of TFG at endoplasmic reticulum exit site (PubMed:27813252). Interacts with SEC16B (PubMed:21478858).
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