Anti-TGFB Recombinant Antibody Products

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Anti-TGFB Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs is at the forefront of developing high-quality anti-TGFβ recombinant antibody products, engineered to meet the diverse and stringent demands of global research and therapeutic development. Our comprehensive portfolio offers unparalleled specificity and efficacy, empowering scientists worldwide to accelerate breakthroughs in critical disease areas.

TGFB: a Versatile Target for Cancer Immunotherapy and Fibrotic Diseases

Transforming Growth Factor-β (TGF-β) is a pleiotropic cytokine with critical roles in cell proliferation, differentiation, apoptosis, and immune responses. While it can act as a tumor suppressor in early cancer stages, it often promotes tumor progression, metastasis, and drug resistance in advanced cancers by shaping the tumor microenvironment. Beyond oncology, dysregulated TGF-β signaling is a central driver of fibrogenesis across various organs, leading to excessive extracellular matrix accumulation and organ dysfunction. Understanding and modulating TGF-β pathways is therefore crucial for developing novel treatments for cancer and fibrotic disorders.

Alternative Names

Transforming growth factor beta; TGF-β; TGFbeta; TGFβ.

Background

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.

Anti-TGFB rAb Products

Creative Biolabs offers a series of anti-TGFB recombinant antibodies that are meticulously engineered to deliver superior performance. These antibodies exhibit high affinity and specificity, thereby facilitating the precise targeting of TGFB isoforms. Leveraging advanced recombinant technology, our antibody production ensures exceptional batch-to-batch consistency and purity, attributes that are indispensable for obtaining reliable and reproducible experimental outcomes and for their potential utility in clinical applications.

Table 1. Featured anti-TGFB recombinant antibody products at Creative Biolabs.

Creative Quality Control

At Creative Biolabs, we rigorously adhere to quality control protocols when performing production. The anti-TGFB recombinant antibodies produced by our facility are subjected to comprehensive, multi-faceted analytical procedures, encompassing techniques such as ELISA, flow cytometry, and bioactivity assays, thereby ensuring their optimal performance. Furthermore, each production lot undergoes meticulous validation for purity, specificity, and functional activity, which collectively guarantees the provision of consistent, high-quality reagents essential for diverse research and development applications.

Customer Reviews

Excellent

Am***a
Human Anti-TGFB Recombinant Antibody (HPAB-0020-YC) (CAT#: HPAB-0020-YC)

The anti-TGFB recombinant antibody from Creative Biolabs has significantly advanced our cancer immunotherapy research. Its consistent performance and high specificity have provided reliable data, accelerating our understanding of TGFB’s role in the tumor microenvironment.

18/Jul/2024

Excellent

Le***s
Mouse Anti-TGFB Recombinant Antibody (clone YC140) (MOB-086LC)

Using Creative Biolabs' anti-TGFB antibody in our fibrosis models has been a game-changer. The antibody's exceptional purity and activity allowed us to achieve clear, reproducible results, which were crucial for our mechanistic studies. It's a top-tier product that truly delivers on its promises for challenging applications.

11/Nov/2024

Excellent

Ja***n
Human Anti-TGFB Recombinant Antibody (HPAB-0019-YC) (CAT#: HPAB-0019-YC)

We've integrated Creative Biolabs' anti-TGFB recombinant antibody into our drug screening platform, and the results have been outstanding. Its robust performance across various assays, from binding studies to cell-based functional tests, has streamlined our workflow and enhanced the reliability of our therapeutic candidate identification.

22/Feb/2025

rAb Production

Our anti-TGFB recombinant antibodies are produced using state-of-the-art recombinant technology and mammalian expression systems, ensuring native folding and post-translational modifications for optimal biological activity. This robust production platform allows for scalable manufacturing while maintaining stringent quality standards, delivering a consistent supply of high-performance antibodies for diverse research needs.

Featured Anti-TGFB Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-TGFB recombinant antibody production.

Fig.2 Gram-scale anti-TGFB recombinant antibody production.

rAb Modalities

Creative Biolabs offers anti-TGFB recombinant antibodies in multiple modalities, including monoclonal, bispecific, engineered antibody fragments, and many others, providing versatile tools for various research and therapeutic strategies.

Fig.3 Full-length anti-TGFB recombinant antibody production and modalities.

TGFB-Targeted Drug Information

Table 2. Public drug targeting TGFB.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

At Creative Biolabs, we are dedicated to supporting your scientific endeavors with cutting-edge solutions. Explore our comprehensive range of anti-TGFB recombinant antibody products today and discover how they can empower your next breakthrough. For detailed product information or to discuss your specific project requirements, please do not hesitate to get in touch with us.

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