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TLR7
Loading...Anti-TLR7 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, FC, ICC, IF
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- Rabbit Anti-TLR7 Recombinant Antibody (clone JA93-11) (MRO-1503-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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- Rabbit Anti-TLR7 Polyclonal Antibody (MRO-2227-CN) (MRO-2227-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
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- Mouse Anti-TLR7 Recombinant Antibody (clone LTM3) (VS11-QX137)
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- Derivation: Mouse
- Species Reactivity: Human, Monkey
- Type: Mouse IgG1, κ
- Application: ELISA, FC
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- Mouse Anti-TLR7 Recombinant Antibody (HPAB-0115-WJ) (HPAB-0115-WJ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IP, FC, IF
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- Mouse Anti-TLR7 Recombinant Antibody; scFv Fragment (HPAB-0115-WJ-S(P)) (HPAB-0115-WJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, WB
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- Mouse Anti-TLR7 Recombinant Antibody; Fab Fragment (HPAB-0115-WJ-F(E)) (HPAB-0115-WJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, WB
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- Mouse Anti-TLR7 Recombinant Antibody (clone 3A9E11) (VS7-0425-WR1003)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
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- Mouse Anti-TLR7 Recombinant Antibody (clone 4G1D4) (VS7-0425-WR1004)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ICC, FC
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- Species Reactivity: Human
- Target: TLR7
- Host Animal: Mouse
- Application: ELISA, FC, Cell-uptake
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- Anti-TLR7 Immunohistochemistry Kit (VS-0525-XY7312)
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- Species Reactivity: Human
- Target: TLR7
- Application: IHC
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- Chicken Anti-TLR7 Polyclonal IgY (BRD-0590MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
Protein class
FDA approved drug targets
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Hofbauer cells, dendritic cells, Macrophages, Microglial cells, monocytes, B-cells)
Immune cell specificity
Immune cell enhanced (plasmacytoid DC)
Cell line specificity
Group enriched (Daudi, U-266/70)
Interaction
Homodimer (PubMed:27742543). Interacts with MYD88 via their respective TIR domains (Probable). Interacts with UNC93B1 (PubMed:33432245). Interacts with SMPDL3B (By similarity).
Molecular function
Receptor
More Types Infomation
Related Signaling Pathways
NLR Signaling Pathway
TLR Signaling Pathway