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Anti-TLR7 Recombinant Antibody Products

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Anti-TLR7 Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs proudly offers a comprehensive portfolio of anti-TLR7 recombinant antibody products, meticulously engineered to meet the stringent demands of global research and therapeutic development. Our advanced antibodies provide unparalleled specificity and affinity, empowering scientists worldwide to accelerate their studies and discover novel insights into immune regulation and disease pathology.

TLR7: A Promising Therapeutic Target for Autoimmune Diseases

Toll-like receptor 7 (TLR7) is a pivotal endosomal pattern recognition receptor central to innate immunity, primarily recognizing viral and self-derived single-stranded RNA. Extensive research highlights its critical role in initiating inflammatory responses and type I interferon production. Dysregulation and overactivation of TLR7 are strongly implicated in the pathogenesis of various autoimmune diseases, particularly Systemic Lupus Erythematosus (SLE). Consequently, understanding and targeting TLR7 is crucial for developing innovative therapeutic strategies against these debilitating conditions.

Alternative Names

Toll-like receptor 7; TLR7-like; toll like receptor 7; IMD74; SLEB17.

Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.

Protein class

FDA approved drug targets

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Hofbauer cells, dendritic cells, Macrophages, Microglial cells, monocytes, B-cells)

Immune cell specificity

Immune cell enhanced (plasmacytoid DC)

Cell line specificity

Group enriched (Daudi, U-266/70)

Interaction

Homodimer (PubMed:27742543). Interacts with MYD88 via their respective TIR domains (Probable). Interacts with UNC93B1 (PubMed:33432245). Interacts with SMPDL3B (By similarity).

Molecular function

Receptor

More Types Infomation

Anti-TLR7 rAb Products

Our anti-TLR7 recombinant antibody products represent a significant advancement in immunological research tools. Leveraging state-of-the-art recombinant technology, these antibodies offer superior batch-to-batch consistency, high purity, and exceptional specificity. Their enhanced binding affinity and low immunogenicity make them ideal for a broad spectrum of applications, ensuring reliable and reproducible results in even the most demanding experimental setups.

Table 1. Featured anti-TLR7 recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
HPAB-0115-WJ Mouse Anti-TLR7 Recombinant Antibody (HPAB-0115-WJ) Human Mouse IgG1 ELISA, WB, IP, FC, IF
ZG-151R Mouse Anti-TLR7 Recombinant Antibody (ZG-151R) Human Mouse IgG WB
ZG-0594U Rabbit Anti-TLR7 Recombinant Antibody (clone 6E5) Human Rabbit IgG ELISA, IHC
VS7-0425-WR1003 Mouse Anti-TLR7 Recombinant Antibody (clone 3A9E11) Human Mouse IgG FC
MOB-1643z Mouse Anti-TLR7 Recombinant Antibody (clone 20G11) Human Mouse IgG1, κ WB, ELISA, FC, ICC, IF

Creative Quality Control

At Creative Biolabs, our anti-TLR7 recombinant antibodies undergo rigorous, multi-faceted quality control measures, including comprehensive specificity testing, affinity determination, and functional validation. Each batch is meticulously assessed for purity via SDS-PAGE and HPLC, and for endotoxin levels, guaranteeing products of the highest standard suitable for sensitive research and in vivo applications.

Fig.1 WB analysis. (Creative Biolabs Original)Fig.1 WB analysis of anti-TLR7 antibody
(Cat# ZG-151R, Creative Biolabs).

Fig.2 IHC analysis. (Creative Biolabs Original)Fig.2 IHC analysis of anti-TLR7 antibody
(Cat# ZG-0594U, Creative Biolabs).

Customer Reviews

Excellent
Al***d
Mouse Anti-TLR7 Recombinant Antibody (clone 20G11) (MOB-1643z)
The anti-TLR7 recombinant antibody from Creative Biolabs significantly enhanced our experimental outcomes. Its exceptional specificity and low background noise streamlined our flow cytometry analysis, saving us considerable time and resources. We achieved clear, interpretable data, which was crucial for advancing our project on autoimmune mechanisms.
25/Oct/2023
Excellent
Ya***i
Recombinant Mouse anti-Human TLR7 Monoclonal antibody (4G6) (MOB-2060CT)
Using Creative Biolabs' anti-TLR7 antibody was a seamless experience. The product arrived promptly, and its performance in our ELISA assays was consistently superior to other antibodies we've used. The high sensitivity allowed us to detect subtle changes in TLR7 expression, providing valuable insights for our therapeutic development work.
11/Aug/2024
Excellent
Wi***t
Rabbit Anti-TLR7 Polyclonal Antibody (MRO-2227-CN) (MRO-2227-CN)
This anti-TLR7 antibody has proven invaluable in our in vivo studies. Its robust performance and excellent stability have consistently delivered reliable results, even under challenging experimental conditions. We've successfully applied it in immunohistochemistry and Western blot, confirming its versatility and high quality across different research applications.
20/Feb/2025

rAb Production

The production of our anti-TLR7 recombinant antibody products is conducted in strict adherence to rigorous protocols, employing advanced recombinant methodologies and mammalian expression systems. This approach facilitates optimal protein folding and post-translational modifications, thereby yielding highly functional antibodies. Furthermore, our scalable manufacturing capabilities ensure a consistent provision of high-quality reagents, thus fulfilling the requirements of both fundamental research and extensive preclinical investigations.

Featured Anti-TLR7 Recombinant Antibody Production PlatformsFig.3 Milligram-scale. (Creative Biolabs Original)
Fig.3 Milligram-scale anti-TLR7 recombinant antibody production.

Fig.4 Gram-scale. (Creative Biolabs Original)Fig.4 Gram-scale anti-TLR7 recombinant antibody production.

rAb Modalities

Our anti-TLR7 recombinant antibodies are available in multiple modalities, including various species origins, isotypes, and conjugation options, providing maximum flexibility for diverse research needs.

Fig.5 TLR7 antibody production and modalities. (Creative Biolabs Original)Fig.5 Full-length anti-TLR7 recombinant antibody production and modalities.

TLR7-Targeted Drug Information

Table 2. Public drug targeting TLR7.

Company Research phase Classification Condition
Daiichi Sankyo (Originator)
University of Tokyo
Phase I/II Monoclonal Antibodies Cutaneous lupus erythematosus
Systemic lupus erythematosus
Novartis (Originator) Phase I Cancer Immunotherapy
Humanized Monoclonal Antibodies
Cancer, solid tumor
Zhejiang University (Originator) Preclinical Cancer Immunotherapy
Liposomes
Monoclonal Antibodies
Cancer, breast
Cancer, solid tumor
Universitaet Bern (Originator) Preclinical Cancer Immunotherapy
Cancer Vaccines
Nanoparticles
Single-stranded oligoribonucleotide (RNA)
Toxins
Virus-Like Particle Vaccines
Cancer
Mosaic ImmunoEngineering (Originator) Preclinical Cancer Immunotherapy
Cancer Vaccines
Cancer
Repertoire Immune Medicines (Originator) Preclinical Cancer Immunotherapy
TCR-Modified T Cells
Melanoma
Altimmune (Originator) Preclinical Cancer Immunotherapy
Cancer Vaccines
Peptide Vaccines
Cancer, colorectal
Cancer, solid tumor
Shandong University (Originator) Preclinical Short Hairpin RNA (shRNA)
Single-stranded oligoribonucleotide (RNA)
Cancer
Sungkyunkwan University (Originator) Biological Testing Coronavirus Vaccines
Nanoparticles
Polypeptides, from 41 AA
Recombinant proteins
Recombinant Vaccines
Coronavirus acute respiratory syndrome
Sungkyunkwan University (Originator) Biological Testing Cancer Immunotherapy
Cancer Vaccines
Nanoparticles
Peptides
Peptide Vaccines
Cancer
Sichuan University (SCU) (Originator) Biological Testing Cancer Immunotherapy
Cancer Vaccines
Extracellular Vesicles
Vaccine Adjuvants
Cancer, breast

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Creative Biolabs is dedicated to advancing scientific discovery by providing premium research reagents. Our anti-TLR7 recombinant antibody products exemplify our commitment to quality and innovation, empowering your breakthroughs in immunology and autoimmune disease research. We invite you to explore our offerings and contact us today to discuss how our expertise can support your next project.

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