


Anti-TLR7 Recombinant Antibody Products

Anti-TLR7 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, FC, ICC, IF
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- Species Reactivity: Human
- Application: ELISA, WB
- Rabbit Anti-TLR7 Recombinant Antibody (clone JA93-11) (MRO-1503-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
- Rabbit Anti-TLR7 Polyclonal Antibody (MRO-2227-CN) (MRO-2227-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
- Mouse Anti-TLR7 Recombinant Antibody (clone LTM3) (VS11-QX137)
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- Derivation: Mouse
- Species Reactivity: Human, Monkey
- Type: Mouse IgG1, κ
- Application: ELISA, FC
- Mouse Anti-TLR7 Recombinant Antibody (HPAB-0115-WJ) (HPAB-0115-WJ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IP, FC, IF
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
- Mouse Anti-TLR7 Recombinant Antibody; scFv Fragment (HPAB-0115-WJ-S(P)) (HPAB-0115-WJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, WB
- Mouse Anti-TLR7 Recombinant Antibody; Fab Fragment (HPAB-0115-WJ-F(E)) (HPAB-0115-WJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, WB
- Mouse Anti-TLR7 Recombinant Antibody (clone 3A9E11) (VS7-0425-WR1003)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
- Mouse Anti-TLR7 Recombinant Antibody (clone 4G1D4) (VS7-0425-WR1004)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ICC, FC
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- Species Reactivity: Human
- Target: TLR7
- Host Animal: Mouse
- Application: ELISA, FC, Cell-uptake
- Anti-TLR7 Immunohistochemistry Kit (VS-0525-XY7312)
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- Species Reactivity: Human
- Target: TLR7
- Application: IHC
- Chicken Anti-TLR7 Polyclonal IgY (BRD-0590MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
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For Research Use Only. Not For Clinical Use.
Creative Biolabs proudly offers a comprehensive portfolio of anti-TLR7 recombinant antibody products, meticulously engineered to meet the stringent demands of global research and therapeutic development. Our advanced antibodies provide unparalleled specificity and affinity, empowering scientists worldwide to accelerate their studies and discover novel insights into immune regulation and disease pathology.
TLR7: A Promising Therapeutic Target for Autoimmune Diseases
Toll-like receptor 7 (TLR7) is a pivotal endosomal pattern recognition receptor central to innate immunity, primarily recognizing viral and self-derived single-stranded RNA. Extensive research highlights its critical role in initiating inflammatory responses and type I interferon production. Dysregulation and overactivation of TLR7 are strongly implicated in the pathogenesis of various autoimmune diseases, particularly Systemic Lupus Erythematosus (SLE). Consequently, understanding and targeting TLR7 is crucial for developing innovative therapeutic strategies against these debilitating conditions.
Alternative Names
Toll-like receptor 7; TLR7-like; toll like receptor 7; IMD74; SLEB17.
Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
FDA approved drug targets
Membrane
Cell type enhanced (Hofbauer cells, dendritic cells, Macrophages, Microglial cells, monocytes, B-cells)
Immune cell enhanced (plasmacytoid DC)
Group enriched (Daudi, U-266/70)
Homodimer (PubMed:27742543). Interacts with MYD88 via their respective TIR domains (Probable). Interacts with UNC93B1 (PubMed:33432245). Interacts with SMPDL3B (By similarity).
Receptor
Anti-TLR7 rAb Products
Our anti-TLR7 recombinant antibody products represent a significant advancement in immunological research tools. Leveraging state-of-the-art recombinant technology, these antibodies offer superior batch-to-batch consistency, high purity, and exceptional specificity. Their enhanced binding affinity and low immunogenicity make them ideal for a broad spectrum of applications, ensuring reliable and reproducible results in even the most demanding experimental setups.
Table 1. Featured anti-TLR7 recombinant antibody products at Creative Biolabs.
Cat. No. | Product Name | Target Species | Host Species | Applications |
HPAB-0115-WJ | Mouse Anti-TLR7 Recombinant Antibody (HPAB-0115-WJ) | Human | Mouse IgG1 | ELISA, WB, IP, FC, IF |
ZG-151R | Mouse Anti-TLR7 Recombinant Antibody (ZG-151R) | Human | Mouse IgG | WB |
ZG-0594U | Rabbit Anti-TLR7 Recombinant Antibody (clone 6E5) | Human | Rabbit IgG | ELISA, IHC |
VS7-0425-WR1003 | Mouse Anti-TLR7 Recombinant Antibody (clone 3A9E11) | Human | Mouse IgG | FC |
MOB-1643z | Mouse Anti-TLR7 Recombinant Antibody (clone 20G11) | Human | Mouse IgG1, κ | WB, ELISA, FC, ICC, IF |
Creative Quality Control
At Creative Biolabs, our anti-TLR7 recombinant antibodies undergo rigorous, multi-faceted quality control measures, including comprehensive specificity testing, affinity determination, and functional validation. Each batch is meticulously assessed for purity via SDS-PAGE and HPLC, and for endotoxin levels, guaranteeing products of the highest standard suitable for sensitive research and in vivo applications.
Fig.1 WB analysis of anti-TLR7 antibody
(Cat# ZG-151R, Creative Biolabs).
Fig.2 IHC analysis of anti-TLR7 antibody
(Cat# ZG-0594U, Creative Biolabs).
Customer Reviews

Mouse Anti-TLR7 Recombinant Antibody (clone 20G11) (MOB-1643z)

Recombinant Mouse anti-Human TLR7 Monoclonal antibody (4G6) (MOB-2060CT)

Rabbit Anti-TLR7 Polyclonal Antibody (MRO-2227-CN) (MRO-2227-CN)
rAb Production
The production of our anti-TLR7 recombinant antibody products is conducted in strict adherence to rigorous protocols, employing advanced recombinant methodologies and mammalian expression systems. This approach facilitates optimal protein folding and post-translational modifications, thereby yielding highly functional antibodies. Furthermore, our scalable manufacturing capabilities ensure a consistent provision of high-quality reagents, thus fulfilling the requirements of both fundamental research and extensive preclinical investigations.
Featured Anti-TLR7 Recombinant Antibody Production Platforms
Fig.3 Milligram-scale anti-TLR7 recombinant antibody production.
Fig.4 Gram-scale anti-TLR7 recombinant antibody production.
rAb Modalities
Our anti-TLR7 recombinant antibodies are available in multiple modalities, including various species origins, isotypes, and conjugation options, providing maximum flexibility for diverse research needs.
Fig.5 Full-length anti-TLR7 recombinant antibody production and modalities.
TLR7-Targeted Drug Information
Table 2. Public drug targeting TLR7.
Company | Research phase | Classification | Condition |
Daiichi Sankyo (Originator) University of Tokyo |
Phase I/II | Monoclonal Antibodies |
Cutaneous lupus erythematosus Systemic lupus erythematosus |
Novartis (Originator) | Phase I |
Cancer Immunotherapy Humanized Monoclonal Antibodies |
Cancer, solid tumor |
Zhejiang University (Originator) | Preclinical |
Cancer Immunotherapy Liposomes Monoclonal Antibodies |
Cancer, breast Cancer, solid tumor |
Universitaet Bern (Originator) | Preclinical |
Cancer Immunotherapy Cancer Vaccines Nanoparticles Single-stranded oligoribonucleotide (RNA) Toxins Virus-Like Particle Vaccines |
Cancer |
Mosaic ImmunoEngineering (Originator) | Preclinical |
Cancer Immunotherapy Cancer Vaccines |
Cancer |
Repertoire Immune Medicines (Originator) | Preclinical |
Cancer Immunotherapy TCR-Modified T Cells |
Melanoma |
Altimmune (Originator) | Preclinical |
Cancer Immunotherapy Cancer Vaccines Peptide Vaccines |
Cancer, colorectal Cancer, solid tumor |
Shandong University (Originator) | Preclinical |
Short Hairpin RNA (shRNA) Single-stranded oligoribonucleotide (RNA) |
Cancer |
Sungkyunkwan University (Originator) | Biological Testing |
Coronavirus Vaccines Nanoparticles Polypeptides, from 41 AA Recombinant proteins Recombinant Vaccines |
Coronavirus acute respiratory syndrome |
Sungkyunkwan University (Originator) | Biological Testing |
Cancer Immunotherapy Cancer Vaccines Nanoparticles Peptides Peptide Vaccines |
Cancer |
Sichuan University (SCU) (Originator) | Biological Testing |
Cancer Immunotherapy Cancer Vaccines Extracellular Vesicles Vaccine Adjuvants |
Cancer, breast |
(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)
Creative Biolabs is dedicated to advancing scientific discovery by providing premium research reagents. Our anti-TLR7 recombinant antibody products exemplify our commitment to quality and innovation, empowering your breakthroughs in immunology and autoimmune disease research. We invite you to explore our offerings and contact us today to discuss how our expertise can support your next project.