Mouse Anti-TLR7 Recombinant Antibody (clone 4G1D4) (CAT#: VS7-0425-WR1004)
This product is a mouse IgG2b antibody that binds to human TLR7. The antibody 4G1D4 recognizes specific amino acid domain of human TLR7 (AA: 420-644). It can be used for ICC and FC assays.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in subsets of non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/ihc_selected.jpg
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in subsets of non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/ihc_selected.jpg
Figure 2 Cerebral cortex
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/132834_B_9_5.jpg
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/132834_B_9_5.jpg
Figure 3 Colon
(Enterocytes - Mucosal lymphoid cells Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/132834_A_9_3.jpg
(Enterocytes - Mucosal lymphoid cells Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/132834_A_9_3.jpg
Figure 4 Kidney
(Distal tubules Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/132834_A_8_5.jpg
(Distal tubules Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/132834_A_8_5.jpg
Figure 5 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/132834_A_7_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/132834_A_7_8.jpg
Figure 6 RNA cell line category: Group enriched (Daudi, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196664-TLR7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196664-TLR7
Specifications
- Immunogen
- Recombinant human TLR7 (AA: 420-644) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human TLR7
- Species Reactivity
- Human
- Clone
- 4G1D4
- Molecule Class
- Toll-Like Receptor
- Applications
- ICC, FC
- Conjugate
- Unconjugated
- Related Disease
- Immunodeficiency 74, COVID19-related, X-linked (IMD74); Systemic lupus erythematosus 17 (SLEB17)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:50 - 1:200
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- TLR7; Toll-Like Receptor 7-Like; Toll-Like Receptor 7; TLR7-Like
- Gene ID
- 51284
- UniProt ID
- Q9NYK1
- Long Name
- Toll like receptor 7
- Cellular Localization
- Cytoplasmic vesicle; Endoplasmic reticulum; Endosome; Lysosome; Membrane
- Post Translation Modifications
- Glycoprotein
- Protein Refseq
- NP_057646.1
- Function
- Receptor
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Related Resources
NLR Signaling Pathway
TLR Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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|---|---|---|---|
| BRD-0590MZ | Chicken Anti-TLR7 Polyclonal IgY | WB | Chicken antibody |
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