Mouse Anti-TLR7 Recombinant Antibody (clone 4G1D4)
CAT#: VS7-0425-WR1004
This product is a mouse IgG2b antibody that binds to human TLR7. The antibody 4G1D4 recognizes specific amino acid domain of human TLR7 (AA: 420-644). It can be used for ICC and FC assays.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in subsets of non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/132834_B_9_5.jpg
Normal Tissue
Figure 3 Colon
Enterocytes - Mucosal lymphoid cells Staining: Low Intensity: Moderate Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/132834_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Distal tubules Staining: Low Intensity: Moderate Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/132834_A_8_5.jpg
Normal Tissue
Figure 5 Lymph node
Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59613/132834_A_7_8.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (Daudi, U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196664-TLR7
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Specifications
- Immunogen
- Recombinant human TLR7 (AA: 420-644) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human TLR7
- Species Reactivity
- Human
- Clone
- 4G1D4
- Molecule Class
- Toll-Like Receptor
- Applications
- ICC, FC
- Conjugate
- Unconjugated
- Related Disease
- Immunodeficiency 74, COVID19-related, X-linked (IMD74); Systemic lupus erythematosus 17 (SLEB17)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:50 - 1:200
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- TLR7; Toll-Like Receptor 7-Like; Toll-Like Receptor 7; TLR7-Like
- Gene ID
- 51284
- UniProt ID
- Q9NYK1
- Long Name
- Toll like receptor 7
- Cellular Localization
- Cytoplasmic vesicle; Endoplasmic reticulum; Endosome; Lysosome; Membrane
- Post Translation Modifications
- Glycoprotein
- Protein Refseq
- NP_057646.1
- Function
- Receptor
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Related Signaling Pathways
NLR Signaling Pathway
TLR Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Reconstitution Buffer
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
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|---|---|---|---|
| BRD-0590MZ | Chicken Anti-TLR7 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
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| MOR-3587 | Rabbit Anti-TLR7 Recombinant Antibody (clone DS3587AB) | WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| MRO-2227-CN | Rabbit Anti-TLR7 Polyclonal Antibody (MRO-2227-CN) | WB, IHC | Rabbit IgG |
| HPAB-0115-WJ | Mouse Anti-TLR7 Recombinant Antibody (HPAB-0115-WJ) | ELISA, WB, IP, FC, IF | Mouse IgG1 |
| VS3-QX1128 | Mouse Anti-TLR7 Recombinant Antibody (clone 3F11-2C9-D8) | WB | Mouse IgG1 |
| VS11-QX137 | Mouse Anti-TLR7 Recombinant Antibody (clone LTM3) | ELISA, FC | Mouse IgG1, κ |
| VS7-0425-WR1003 | Mouse Anti-TLR7 Recombinant Antibody (clone 3A9E11) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0115-WJ-S(P) | Mouse Anti-TLR7 Recombinant Antibody; scFv Fragment (HPAB-0115-WJ-S(P)) | ELISA, FC, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0115-WJ-F(E) | Mouse Anti-TLR7 Recombinant Antibody; Fab Fragment (HPAB-0115-WJ-F(E)) | ELISA, FC, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC630 | Recombinant Anti-TLR7 Vesicular Antibody, EV Displayed (VS-0425-YC630) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7312 | Anti-TLR7 Immunohistochemistry Kit | IHC |
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