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TNF-alpha

Anti-TNF-alpha Products

Mouse Anti-TNF-alpha Recombinant Antibody (VS-0322-LC33) (VS-0322-LC33)
- Species Reactivity: Rabbit
- Application: Neut
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Mouse Anti-TNF-alpha Recombinant Antibody (VS-0322-LC34) (VS-0322-LC34)
- Species Reactivity: Rabbit, Cotton Rat, Feline, Guinea pig, Human, Mouse, Rat, Canine, Equine, Rhesus
- Application: WB
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For Research Use Only. Not For Clinical Use.

Tumor necrosis factor (TNF-alpha ), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily and family. The 26 kDa type II transmembrane protein is assembled intracellularly to form a noncovalently linked homotrimer. Rabbit TNF-alpha is 235 amino acids (aa) in length and contains a 35 aa cytoplasmic domain, a 21 aa transmembrane region, and a 179 extracellular domain (ECD). TNF-alpha is produced by several lymphoid cells as well as by astrocytes, endothelial cells, and smooth muscle cells.

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