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TNNC1

Anti-TNNC1 ProductsBackground
Anti-TNNC1 Products
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- Species Reactivity: Human
- Application: AP, ELISA, IHC-P, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, ELISA, IHC
- AbPlus™ Anti-TNNC1 Magnetic Beads (VS-0724-YC1027) (VS-0724-YC1027)
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- Target: TNNC1
- Target Species: Human, Cynomolgus
- Application: IP, Protein Purification
- Anti-Mouse TNNC1 Immunohistochemistry Kit (VS-0525-XY7401)
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- Species Reactivity: Human, Mouse, Rat
- Target: TNNC1
- Application: IHC
- Anti-TNNC1 Immunohistochemistry Kit (VS-0525-XY7400)
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- Species Reactivity: Human
- Target: TNNC1
- Application: IHC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
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For Research Use Only. Not For Clinical Use.
Background
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Cardiomyocytes)
Immune cell specificity
Immune cell enhanced (MAIT T-cell)
Cell line specificity
Cell line enhanced (CACO-2, CAPAN-2, EFO-21, HeLa, Hep G2, HSkMC, U-2 OS)
Molecular function
Muscle protein
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