AbPlus™ Anti-TNNC1 Magnetic Beads (VS-0724-YC1027) (CAT#: VS-0724-YC1027)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-TNNC1 specific antibody

• Target
• TNNC1

• Immunogen
• Recombinant human Troponin C/TNNC1, aa 1-161.

• Target Species
• Human, Cynomolgus

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]

• Alternative Names
• Troponin C1, Slow Skeletal And Cardiac Type; Troponin C Type 1 (Slow); TN-C; TNNC; Slow Twitch Skeletal/Cardiac Muscle Troponin C; Troponin C, Slow Skeletal And Cardiac Muscles;

• Gene ID
• 7134

• UniProt ID
• P63316

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