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TUB
Loading...Anti-TUB Products
- Anti-TUB Immunohistochemistry Kit (VS-0525-XY7598)
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- Species Reactivity: Human
- Target: TUB
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
Protein class
Disease related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Rod photoreceptor cells, Cone photoreceptor cells, Excitatory neurons, Horizontal cells, Inhibitory neurons, Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HAP1, HEK93, HeLa, SCLC-21H, SH-SY5Y)
Interaction
Interacts with GNAQ. Interacts with TULP1.
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