Anti-TYK2 Recombinant Antibody Products

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Anti-TYK2 Products

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For Research Use Only. Not For Clinical Use.

At Creative Biolabs, we are at the forefront of providing global researchers and pharmaceutical companies with premium anti-TYK2 recombinant antibody products. Engineered for unparalleled specificity and high affinity, our cutting-edge antibodies are indispensable tools for advancing drug discovery and development, facilitating crucial breakthroughs in inflammatory and autoimmune disease research worldwide.

TYK2: A Promising Target for Inflammatory and Autoimmune Therapies

TYK2 (Tyrosine Kinase 2) is a non-receptor tyrosine kinase, a key member of the Janus kinase (JAK) family, playing a pivotal role in the JAK-STAT signaling pathway. It specifically mediates signals from critical cytokines like IL-12, IL-23, and type I interferons, essential for regulating immune responses and inflammatory processes. Extensive research underscores TYK2's significance, particularly as a therapeutic target for autoimmune and inflammatory diseases, offering a selective pathway to modulate detrimental immune hyperactivity.

Alternative Names

Tyrosine kinase 2; non-receptor tyrosine-protein kinase TYK2; IMD35; JTK1; non-receptor tyrosine-protein kinase

Background

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008].

Anti-TYK2 rAb Products

Creative Biolabs' anti-TYK2 recombinant antibodies are engineered with unparalleled precision, leveraging cutting-edge genetic techniques to deliver exceptional purity and unwavering lot-to-lot consistency, ensuring reliable and reproducible results. These antibodies offer superior specificity and binding affinity, critical for reliable and reproducible results in diverse research applications, from preclinical studies to therapeutic development. Their recombinant nature guarantees high functional activity and reduced batch variation compared to traditional polyclonal antibodies.

Table 1. Featured anti-TYK2 recombinant antibody products at Creative Biolabs.

Creative Quality Control

Our anti-TYK2 recombinant antibody products undergo rigorous, multi-faceted quality control measures. We employ comprehensive analytical methods, including ELISA, Western Blot, and flow cytometry, to verify target specificity, binding kinetics, and functional activity. This stringent quality assurance process ensures that every antibody lot meets the highest industry standards, providing researchers with dependable and validated tools for their critical experiments.

Customer Reviews

Excellent

A**a Sh***a
Rabbit Anti-TYK2 Polyclonal Antibody (MRO-2247-CN) (MRO-2247-CN)

The anti-TYK2 recombinant antibody from Creative Biolabs significantly accelerated our in vitro signaling pathway studies. Its high specificity and low background noise were particularly impressive, allowing for crystal-clear data interpretation. We achieved results faster than anticipated, which is invaluable in our fast-paced research environment.

10/May/2024

Excellent

M**k Je***n
Mouse Anti-TYK2 Recombinant Antibody (ZG-0487F) (ZG-0487F)

Our team utilized Creative Biolabs' anti-TYK2 antibody for immunohistochemistry in complex tissue samples. The consistent performance across multiple batches was outstanding, yielding precise and reproducible staining. This consistency is crucial for our translational research, and it has become our go-to reagent for TYK2-related investigations.

5/Jun/2024

Excellent

Ch*n L*
Rabbit Anti-TYK2 Recombinant Antibody (clone DS3732AB) (MOR-3732)

For our therapeutic antibody development program, the anti-TYK2 recombinant antibody's application in functional assays was critical. It demonstrated potent neutralizing activity against TYK2-mediated signaling, validating our experimental models. The ease of use and the detailed product documentation also streamlined our workflow considerably, contributing to a smooth research progression.

22/Apr/2025

rAb Production

Our anti-TYK2 recombinant antibodies are produced through a robust and scalable manufacturing process within state-of-the-art facilities. Leveraging advanced bioreactor technology and proprietary purification techniques, we ensure consistent high yields of pure, active antibody. This optimized production workflow allows us to efficiently meet the demands of both small-scale research and larger preclinical studies, ensuring timely access to essential reagents.

Featured Anti-TYK2 Recombinant Antibody Production Platforms
Fig.2 Milligram-scale anti-TYK2 recombinant antibody production.

Fig.3 Gram-scale anti-TYK2 recombinant antibody production.

rAb Modalities

Our anti-TYK2 recombinant antibodies are offered with a range of formats and modifications, providing versatile options for your research needs. This adaptability allows researchers to select the optimal tool for their specific experimental needs, enhancing research efficiency.

Fig.4 Full-length anti-TYK2 recombinant antibody production and modalities.

TYK2-Targeted Drug Information

Table 2. Public drug targeting TYK2.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Empowering scientific breakthroughs starts with superior reagents. Creative Biolabs' anti-TYK2 recombinant antibodies offer the precise targeting and dependable performance critical for your most ambitious research. Browse our full product line and let our expertise enhance your studies. Reach out to us for more details or to discuss your project's unique demands.

Related Signaling Pathways

JAK-STAT Signaling Pathway

Related Diseases

Pancreatic Cancer