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UBE2J1
Loading...Anti-UBE2J1 Products
- AbPlus™ Anti-UBE2J1 Magnetic Beads (VS-0724-YC238) (VS-0724-YC238)
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- Target: UBE2J1
- Target Species: Human
- Application: IP, Protein Purification
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- Mouse Anti-NHP UBE2J1 Recombinant Antibody (clone OTI3D1) (VS-1024-XY527)
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- Species Reactivity: Dog, Human, Mouse, Non-human primate, Rat
- Type: Mouse IgG2a
- Application: WB, IHC, FC
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For Research Use Only. Not For Clinical Use.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.
Protein class
Enzymes, Metabolic proteins
Predicted location
Membrane
Single cell type specificity
Group enriched (Late spermatids, Plasma cells, Early spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (Daudi, Karpas-707, U-266/70)
Interaction
Component of the HRD1 complex, which comprises at least SYNV1/HRD1, DERL1/2, FAM8A1, HERPUD1/HERP, OS9, SEL1L and UBE2J1 (PubMed:28827405). Interacts with E3 ligase RNF26 (PubMed:33472082).
Molecular function
Transferase
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