UGDH
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Loading...- AbPlus™ Anti-UGDH Magnetic Beads (VS-0724-YC70) (VS-0724-YC70)
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- Target: UGDH
- Target Species: Human
- Application: IP, Protein Purification
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- Mouse Anti-UGDH Recombinant Antibody (clone 2506W62) (VS-0625-FY97)
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- Species Reactivity: Human
- Type: Mouse IgG2b, kappa
- Application: ICC, WB, FC, ELISA
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- Mouse Anti-UGDH Recombinant Antibody (UG106) (VS-0326-YC106)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]