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UPP1

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For Research Use Only. Not For Clinical Use.


Background

This gene encodes a uridine phosphorylase, an enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded enzyme functions in the degradation and salvage of pyrimidine ribonucleosides.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Paneth cells, Extravillous trophoblasts, Distal enterocytes, Macrophages)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enriched (hTERT-HME1)

Interaction

Homodimer.

Molecular function

Glycosyltransferase, Transferase

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