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For Research Use Only. Not For Clinical Use.
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Interacts with SMAD4, MARK4, NUAK1 and BIRC5/survivin. Interacts with DCX. Interacts with OTUD4 and USP7; the interaction is direct (PubMed:25944111). Interacts with ARNTL/BMAL1 (PubMed:29626158). Interacts with RICTOR; the interaction results in deubiquitination of RICTOR and protection from proteasomal degradation (PubMed:33378666).
Hydrolase, Protease, Thiol protease