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XCL1

This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells.
Predicted location

Secreted

Single cell type specificity

Group enriched (T-cells, dendritic cells)

Immune cell specificity

Immune cell enriched (NK-cell)

Cell line specificity

Cell line enhanced (CACO-2, Hep G2, SCLC-21H, SuSa, U-266/70, U-266/84)

Molecular function

Cytokine

More Types Infomation

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