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For Research Use Only. Not For Clinical Use.


Background

It has chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Predicted location

Secreted

Single cell type specificity

Group enriched (T-cells, dendritic cells)

Immune cell specificity

Immune cell enriched (NK-cell)

Cell line specificity

Cell line enhanced (CACO-2, Hep G2, SCLC-21H, SuSa, U-266/70, U-266/84)

Molecular function

Cytokine

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