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YY1
Anti-YY1 Recombinant Antibody Products
- Rabbit Anti-YY1 Recombinant Antibody (clone CBACN-587) (MRO-1609-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP
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- Mouse Anti-YY1 Recombinant Antibody (VS3-CJ821) (VS3-CJ821)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, IHC
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- Rabbit Anti-YY1 Recombinant Antibody (VS3-CJ822) (VS3-CJ822)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, IP
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- Recombinant Rabbit Anti-YY1 Antibody (clone R01-1D3) (VS3-FY1571)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IP
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- Mouse Anti-YY1 Recombinant Antibody (clone 29H6) (MOB-2865z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, ICC, IF, IHC
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For Research Use Only. Not For Clinical Use.
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq, Jul 2008]
Protein class
Disease related genes, Human disease related genes, Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with YAF2 through the region encompassing the first and second zinc fingers (PubMed:9016636). Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80 (PubMed:17721549, PubMed:18026119, PubMed:18922472, PubMed:21303910). Interacts with EED and EZH2; the interactions are indicative for an association with the PRC2/EED-EZH2 complex (PubMed:11158321). Interacts with SFMBT2 (PubMed:23385818). Found in a complex with SMAD1 and SMAD4 (PubMed:15329343). Found in a complex with YY1, SIN3A and HDAC1 (By similarity).
Molecular function
Activator, DNA-binding, Repressor
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Related Signaling Pathways
mTOR Signaling Pathway