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ZMPSTE24

Formats

Anti-ZMPSTE24 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.
Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Transporters

Predicted location

Membrane

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Molecular function

Hydrolase, Metalloprotease, Protease

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