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    Recombinant Human Anti-human ZMPSTE24 Antibody (CAT#: MHH-1057)

    Recombinant Human Antibody is bind to Human ZMPSTE24, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-ZMPSTE24 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-ZMPSTE24 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

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    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IHC staining of human stomach
    Figure 1 IHC staining of human stomach
    (Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/ihc_selected.jpg
    Normal Tissue
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Glial cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Neuropil
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_B_7_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Glandular cells
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_A_9_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Cholangiocytes
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Hepatocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_A_8_4.jpg
    Figure 5 Prostate
    Figure 5 Prostate
    (Glandular cells
    Staining: Low
    Intensity: Weak
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_A_3_5.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in glomeruli
    Staining: Low
    Intensity: Weak
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Cells in tubules
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_A_9_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Cells in seminiferous ducts
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_A_5_6.jpg
    Figure 8 Lymph node
    Figure 8 Lymph node
    (Germinal center cells
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_A_8_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Low cell line specificity
    Figure 9 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000084073-ZMPSTE24/subcellular

    Specifications

    • Immunogen
    • Human zinc metallopeptidase STE24
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • IgG
    • Specificity
    • Tested positive against native Human zinc metallopeptidase STE24
    • Species Reactivity
    • Human
    • Applications
    • Products can be used for: Western blot; Flow Cytometry; Functional Study

    Product Property

    • Purity
    • 95% by HPLC
    • Storage
    • ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C

    Target

    • Alternative Names
    • ZMPSTE24; zinc metallopeptidase STE24; HGPS; PRO1; FACE1; STE24; FACE-1; Ste24p; CAAX prenyl protease 1 homolog; zinc metallopeptidase STE24 homolog; zinc metalloproteinase Ste24 homolog; prenyl protein-specific endoprotease 1; farnesylated proteins-conve

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    IgG Antibody Products Fab Antibody Products ScFv Antibody Products IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
    CAT Product Name Application Type
    MOB-1057 Recombinant Anti-human ZMPSTE24 Antibody WB, ELISA, IHC, FuncS IgG

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