Recombinant Human Anti-human ZMPSTE24 Antibody
CAT#: MHH-1057
Recombinant Human Antibody is bind to Human ZMPSTE24, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-ZMPSTE24 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-ZMPSTE24 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_A_8_4.jpg
Normal Tissue
Figure 5 Prostate
Glandular cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_A_3_5.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_A_9_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_A_5_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6988/18704_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000084073-ZMPSTE24/subcellular
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❯
Specifications
- Immunogen
- Human zinc metallopeptidase STE24
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human zinc metallopeptidase STE24
- Species Reactivity
- Human
- Applications
- Products can be used for: Western blot; Flow Cytometry; Functional Study
Product Property
- Purity
- 95% by HPLC
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
- Alternative Names
- ZMPSTE24; zinc metallopeptidase STE24; HGPS; PRO1; FACE1; STE24; FACE-1; Ste24p; CAAX prenyl protease 1 homolog; zinc metallopeptidase STE24 homolog; zinc metalloproteinase Ste24 homolog; prenyl protein-specific endoprotease 1; farnesylated proteins-conve
- Gene ID
- 10269
- UniProt ID
- O75844
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ZMPSTE24"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1057 | Recombinant Anti-human ZMPSTE24 Antibody | WB, ELISA, IHC, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1057-F(E) | Recombinant Anti-human ZMPSTE24 Antibody Fab Fragment | RIA, IP, FuncS | Fab |
| MHH-1057-F(E) | Recombinant Human Anti-human ZMPSTE24 Antibody Fab Fragment | RIA, IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1057-S(P) | Recombinant Anti-human ZMPSTE24 Antibody scFv Fragment | IF, Neut, FuncS | scFv |
| MHH-1057-S(P) | Recombinant Human Anti-human ZMPSTE24 Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2536 | Anti-ZMPSTE24 Immunohistochemistry Kit | IHC |
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