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IL36RN
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- Anti-Human IL36RN Recombinant Antibody (TAB-430CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
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- Human Anti-IL36RN Antibody, mRNA (TAB-430CL-mRNA)
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- Species Reactivity: Human
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For Research Use Only. Not For Clinical Use.
The anti-IL-36R antibodies can be used in pharmaceutical compositions and kits comprising such compounds. The antibodies are useful in methods for the treatment of various diseases or disorders, for example immunological, inflammatory, autoimmune, fibrotic and respiratory diseases in humans.
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Cytotrophoblasts, Syncytiotrophoblasts, Extravillous trophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (BEWO, GAMG, U-87 MG)
Interaction
Interacts with cargo receptor TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion.
Molecular function
Cytokine
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