Tumor-infiltrating Lymphocyte Antibody Panel (CD3E, CD4, CD8A, MS4A1)
CAT#: VS-0725-YC26
The Tumor-infiltrating Lymphocyte Antibody Panel are sets of 4 highly validated antibodies, specifically designed for the simultaneous detection of key lymphocyte subsets within tumor tissues. Included in this essential set are antibodies against CD3E (pan T-cell marker), CD4 (helper T-cells), CD8A (cytotoxic T-cells), and MS4A1 (B-cells). This panel provides a powerful and streamlined tool for characterizing immune cell infiltration in oncology research, enabling a deeper understanding of anti-tumor immunity.
Sub Cat | Component Name | Clone | Type | Target | Species Reactivity | Applications | |
VS-0725-YC161 | Rabbit Anti-CD3E Recombinant Antibody | Rabbit IgG | CD3E | Human | FC, ICC, IF, IHC, IP, WB | ||
VS-0725-YC162 | Rabbit Anti-CD8A Recombinant Antibody | Rabbit IgG | CD8A | Human | IHC | ||
VS-0725-YC163 | Rabbit Anti-CD4 Recombinant Antibody | Rabbit IgG | CD4 | Human | FC, IHC, IP, WB | ||
VS-0725-YC164 | Rabbit Anti-MS4A1 Recombinant Antibody | Rabbit IgG | MS4A1 | Human | FC, ICC, IF, IHC, IP |
Specifications
- Targets
- CD3E, CD4, CD8A, MS4A1
- Species Reactivity
- Human
- Research Area
- Tumor-infiltrating Lymphocyte
- Introduction
- Tumor-infiltrating lymphocytes (TILs) represent a diverse and dynamic population of immune cells that have migrated from the bloodstream into the tumor microenvironment (TME) of solid tumors. Comprising primarily T cells (both CD4+ helper and CD8+ cytotoxic T cells), B cells, and Natural Killer (NK) cells, TILs signify an ongoing immune response against the developing or established malignancy. Their presence, composition, spatial distribution, and functional status within the tumor are increasingly recognized as powerful prognostic and predictive biomarkers, playing a pivotal role in the effectiveness of contemporary cancer immunotherapies.
- Storage
- Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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