A*0201/HPV16 E7 (DLLLGTLNI) MHC Tetramer

CAT#: MHC-LC751

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HPV16-derived peptide of DLLLGTLNI sequence covering 81-89 and A*0201 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specifications

  • Allele
  • A*0201
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • HPV16 E7
  • Antigen Species
  • HPV16
  • Peptide
  • DLLLGTLNI
  • Range
  • 81-89
  • Application
  • FCM

Target

  • Antigen Introduction
  • Papillomaviridae is an ancient taxonomic family of non-enveloped DNA viruses, collectively known as papillomaviruses. Several hundred species of papillomaviruses, traditionally referred to as "types", have been identified infecting all carefully inspected mammals, but also other amniotes such as birds, snakes and turtles. Infection by most papillomavirus types, depending on the type, is either asymptomatic (e.g. most Beta-PVs) or causes small benign tumors, known as papillomas or warts (e.g. human papillomavirus1, HPV6 or HPV11). Papillomas caused by some types, however, such as human papillomaviruses 16 and 18, carry a risk of becoming cancerous.
  • Alternative Names
  • HPV16 E7; Human papillomavirus type 16 E7
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