Recombinant Anti-HPV16 E7 Intrabody [(D-Arg)₉] (CAT#: IAB-B047(A))

• Immunogen
• Human papillomavirus16 transforming protein

• Host Species
• mouse

• Type
• scFv-(D-Arg)₉

• Cell Penetrating Peptide
• (D-Arg)₉
  It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.

• Species Reactivity
• HPV16

• Applications
• Products can be used for: Immunocytochemistry; Neutralization; Functional studies

• Purity
• >95% as determined by analysis by SDS-PAGE

• Storage
• Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

• Alternative Names
• E7; transforming protein

• Gene ID
• 1489079

• UniProt ID
• P03129

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