APC-A*01:01/Human MAGEA3 (ESDPIVAQY) MHC Tetramer (CAT#: MHC-LC927)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of MAGEA3-derived peptide of ESDPIVAQY covering 168-176 and A*01:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (GAMG, K-562, OE19, PC-3, SH-SY5Y, SK-BR-3, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000221867-MAGEA3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000221867-MAGEA3
Specifications
- Allele
- A*01:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- MAGE-A3
- Antigen Species
- Human
- Peptide
- ESDPIVAQY
- Range
- 168-176
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
- Alternative Names
- MAGEA3; MAGE family member A3; HIP8; HYPD; CT1.3; MAGE3; MAGEA6
- Gene ID
- 4102
- UniProt ID
- P43357
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2790z | Mouse Anti-MAGEA3 Recombinant Antibody (clone 6B5) | WB, IHC | Mouse IgG2a |
| HPAB-0183-LSX | Human Anti-MAGEA3 Recombinant Antibody (clone 21B4) | ELISA, WB, IP, FC, IHC | Human IgG |
| HPAB-0184-LSX | Human Anti-MAGEA3 Recombinant Antibody (clone M3H67) | ELISA, WB | Human IgG |
| HPAB-0185-LSX | Human Anti-MAGEA3 Recombinant Antibody (clone 31H10) | ELISA, IP, WB, FC | Human IgG |
| VS3-FY870 | Recombinant Rabbit Anti-MAGEA3 Antibody (clone R07-8A2) | WB | Rabbit IgG |
Customer Reviews and Q&As
Customer Review
Q&As
Critical for Cancer Immunology
Utilizing this tetramer, we've gained deep insights into hMAGEA3-specific T cell populations. Such specificity is invaluable in our endeavors to develop targeted immunotherapies, providing reliable data to guide vaccine and T cell therapy design.
Trustworthy for Accurate Immune Mapping
Its high specificity allows for precise mapping of immune responses, which is crucial for understanding how tumor antigens like hMAGEA3 are recognized by the immune system, leading to better therapeutic interventions.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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