APC-A*02:01/Human LIVIN (QLCPICRAPV) MHC Tetramer
CAT#: MHC-LC061
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of LIVIN-derived peptide of QLCPICRAPV sequence covering 175-184 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47850/1291_D11_1_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101197-BIRC7
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Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- LIVIN
- Antigen Species
- Human
- Peptide
- QLCPICRAPV
- Range
- 175-184
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants.
- Alternative Names
- BIRC7; Baculoviral IAP repeat containing 7; KIAP; LIVIN; MLIAP; RNF50; ML-IAP
- Gene ID
- 911829
- UniProt ID
- Q05320
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| MHC-LC060 | PE-A*02:01/Human LIVIN (QLCPICRAPV) MHC Tetramer | FCM | |
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