APC-A*02:01/Human IGRP (VLFGLGFAI) MHC Tetramer
CAT#: MHC-LC669
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of IGRP-derived peptide of VLFGLGFAI sequence covering 265-273 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- IGRP
- Antigen Species
- Human
- Peptide
- VLFGLGFAI
- Range
- 265-273
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined.
- Alternative Names
- G6PC2; glucose-6-phosphatase catalytic subunit 2; IGRP
- Gene ID
- 57818
- UniProt ID
- Q9NQR9
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Datasheet
MSDS
COA
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