PE-A*02:01/Human IGRP (VLFGLGFAI) MHC Tetramer (CAT#: MHC-LC668)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of IGRP-derived peptide of VLFGLGFAI sequence covering 265-273 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- IGRP
- Antigen Species
- Human
- Peptide
- VLFGLGFAI
- Range
- 265-273
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined.
- Alternative Names
- G6PC2; glucose-6-phosphatase catalytic subunit 2; IGRP
- Gene ID
- 57818
- UniProt ID
- Q9NQR9
Downloads
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See other products for "G6PC2"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC669 | APC-A*02:01/Human IGRP (VLFGLGFAI) MHC Tetramer | FCM | |
MHC-LC670 | BV421-A*02:01/Human IGRP (VLFGLGFAI) MHC Tetramer | FCM | |
MHC-YF145 | H-2Kd/Human IGRP (VYLKTNVFL) MHC Monomer | MHC Multimer | |
MHC-YF235 | A*02:01/Human IGRP (LNIDLLWSV) MHC Monomer | MHC Multimer | |
MHC-YF274 | A*02:01/Human IGRP (VLFGLGFAI) MHC Monomer | MHC Multimer |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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