APC-A*02:01/Human MAGE-C1 (ILFGISLREV) MHC Tetramer
CAT#: MHC-LC194
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of MAGE-C1-derived peptide of ILFGISLREV sequence covering 959-968 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15452/if_selected.jpg
Normal Tissue
Figure 2 High expression in testis
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4622/162680_A_5_6_selected.jpg
Normal Tissue
Figure 3 Low expression in epididymis
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4622/162680_A_3_6_val_selected.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4622/162680_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4622/162680_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (K-562, Karpas-707, U-2 OS, U-2197, U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000155495-MAGEC1
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Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- MAGE-C1
- Antigen Species
- Human
- Peptide
- ILFGISLREV
- Range
- 959-968
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, and therefore is about 800 aa longer than the other MAGE proteins.
- Alternative Names
- MAGEC1; MAGE family member C1; CT7; CT7.1
- Gene ID
- 9947
- UniProt ID
- O60732
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Datasheet
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COA
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|---|---|---|---|
| MOB-2791z | Mouse Anti-MAGEC1 Recombinant Antibody (clone 44G11) | WB, ELISA, IF, IHC, IP | Mouse IgG1, κ |
| MOB-0320MZ | Recombinant Mouse Anti-Human MAGEC1 Antibody (clone DT8-34) | IHC | Mouse antibody |
| MOB-0092F | Mouse Anti-MAGEC1 Recombinant Antibody (MOB-0092F) | IHC-P, IF | Mouse IgG |
| VS3-CJ160 | Mouse Anti-MAGEC1 Recombinant Antibody (clone ABT-MAGEC1) | WB, IHC-P | Mouse IgG2b, κ |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC193 | PE-A*02:01/Human MAGE-C1 (ILFGISLREV) MHC Tetramer | FCM | |
| MHC-CN1021 | PE-A*02:01/Human MAGEC1 (FLAMLKNTV) MHC Tetramer | FCM, IHC | |
| MHC-CN1022 | APC-A*02:01/Human MAGEC1 (FLAMLKNTV) MHC Tetramer | FCM, IHC | |
| MHC-CN1023 | FITC-A*02:01/Human MAGEC1 (FLAMLKNTV) MHC Tetramer | FCM, IHC | |
| MHC-CN1024 | A*02:01/Human MAGEC1 (FLAMLKNTV) MHC Tetramer | FCM, IHC |
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