APC-A*02:01/Human MAGE-C1 (ILFGISLREV) MHC Tetramer (CAT#: MHC-LC194)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of MAGE-C1-derived peptide of ILFGISLREV sequence covering 959-968 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15452/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15452/if_selected.jpg
Figure 2 High expression in testis
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4622/162680_A_5_6_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4622/162680_A_5_6_selected.jpg
Figure 3 Low expression in epididymis
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4622/162680_A_3_6_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4622/162680_A_3_6_val_selected.jpg
Figure 4 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4622/162680_A_8_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4622/162680_A_8_5.jpg
Figure 5 Testis
(Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4622/162680_A_6_6.jpg
(Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4622/162680_A_6_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (K-562, Karpas-707, U-2 OS, U-2197, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000155495-MAGEC1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000155495-MAGEC1
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- MAGE-C1
- Antigen Species
- Human
- Peptide
- ILFGISLREV
- Range
- 959-968
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, and therefore is about 800 aa longer than the other MAGE proteins.
- Alternative Names
- MAGEC1; MAGE family member C1; CT7; CT7.1
- Gene ID
- 9947
- UniProt ID
- O60732
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2791z | Mouse Anti-MAGEC1 Recombinant Antibody (clone 44G11) | WB, ELISA, IF, IHC, IP | Mouse IgG1, κ |
| MOB-0092F | Mouse Anti-MAGEC1 Recombinant Antibody (MOB-0092F) | IHC-P, IF | Mouse IgG |
| VS3-CJ160 | Mouse Anti-MAGEC1 Recombinant Antibody (clone ABT-MAGEC1) | WB, IHC-P | Mouse IgG2b, κ |
| VS3-CJ161 | Mouse Anti-MAGEC1 Recombinant Antibody (VS3-CJ161) | WB, IHC | Mouse IgG2b |
| VS3-FY871 | Recombinant Mouse Anti-MAGEC1 Antibody (clone 8C5-8G7-4F4) | IHC-P | Mouse IgG2b |
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