Mouse Anti-α5β1 Recombinant Antibody (clone SG/19); Fab Fragment

CAT#: PFBL-741

Recombinant Mouse Antibody (SG/19) is capable of binding to α5β1.

Specifications

  • Immunogen
  • Human Alpha-5 beta-1
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • Mouse Fab
  • Specificity
  • Human α5β1
  • Species Reactivity
  • Human
  • Clone
  • SG/19
  • Applications
  • WB, ELISA, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Alpha-5 beta-1; α5β1; integrin
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Breast cancer biomarkers at key points during disease progression
Exceptional specificity
I've been using this Fab fragment for almost a year in our cancer metastasis studies, and its specificity for integrin α5β1 has been exceptional. Highly recommend it for anyone needing reliable antibodies for cell adhesion research.
Breast cancer biomarkers at key points during disease progression
Suitable to live cell imaging
In live cell imaging, the signal specificity provided by this Fab fragment is outstanding. It has enabled us to better visualize integrin α5β1 activity in real-time with minimal non-specific binding.
Breast cancer biomarkers at key points during disease progression
No cross-reactivity
No cross-reactivity issues whatsoever - truly specific to integrin α5β1. This high specificity has been crucial for our studies, reducing the likelihood of misleading results.

Q&As

  1. What is the precise binding of the Fab fragment of Mouse Anti-α5β1 Recombinant Antibody (clone SG/19)?

    A: This antibody binds to the integrin α5β1 receptor, which is essential for cell adhesion and migration, especially in cancer metastasis and angiogenesis.

  2. Why is the Fab segment of clone SG/19 so successful in interacting with integrin α5β1?

    A: Clone SG/19's Fab fragment lacks an Fc region, which reduces background interference and off-target binding. This property makes it ideal for high-precision applications like immunohistochemistry and flow cytometry.

  3. In live cell imaging experiments, what is the performance of the it?

    A: This recombinant antibody performs remarkably well in live cell imaging experiments, producing clear and specific signals due to its high affinity and low non-specific binding.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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