Afuco™ Anti-Human ADGRE1 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-019CL)
Anti-ADGRE1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. Antibodies that bind to EMR1 are known. However, there is a need for the development of therapeutic antibodies that selectively target EMR-1 and deplete eosinophils.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Colon
(Glandular cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52809/119726_A_8_3.jpg
(Glandular cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52809/119726_A_8_3.jpg
Figure 2 Bone marrow
(Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52809/119726_B_5_4.jpg
(Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52809/119726_B_5_4.jpg
Figure 3 RNA cell line category: Cell line enhanced (A549, BJ hTERT+, GAMG, HDLM-2, HMC-1, Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174837-ADGRE1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174837-ADGRE1
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- EMR1-related diseases
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- 4°C or -20°C, avoid repeated freezing and thawing.
Target
- Alternative Names
- EMR1; egf-like module containing, mucin-like, hormone receptor-like 1; TM7LN3; EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; EGF-like module receptor 1; egf-like module containing, mucin-like, hormone receptor-like sequence 1
- Gene ID
- 2015
- UniProt ID
- Q14246
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-336MZ | Mouse Anti-ADGRE1 Recombinant Antibody (TAB-336MZ) | ELISA | Mouse IgG |
| TAB-336MZ-S(P) | Mouse Anti-ADGRE1 Recombinant Antibody; scFv Fragment (TAB-336MZ-S(P)) | ELISA | Mouse scFv |
| TAB-337MZ-S(P) | Mouse Anti-ADGRE1 Recombinant Antibody; scFv Fragment (TAB-337MZ-S(P)) | ELISA | Mouse scFv |
| TAB-338MZ-S(P) | Mouse Anti-ADGRE1 Recombinant Antibody; scFv Fragment (TAB-338MZ-S(P)) | ELISA | Mouse scFv |
| TAB-339MZ-S(P) | Mouse Anti-ADGRE1 Recombinant Antibody; scFv Fragment (TAB-339MZ-S(P)) | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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