Human Anti-CD18 Recombinant Antibody (clone H52) (CAT#: PABZ-019)
Recombinant Humanized Antibody (H52) is capable of binding to CD18, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-CD18 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-CD18 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. The humanization of the anti-CD18 antibody H52 was hampered by not appreciating the possibilitythat residues in the C-terminal part of CDR-H2could be important in antigen binding.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Immunogen
- Human integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
- Host Species
- Human
- Derivation
- Humanized
- Type
- Human IgG
- Specificity
- CD18
- Species Reactivity
- Human
- Clone
- H52
- Applications
- FC
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ITGB2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1; integrin beta-2; integrin beta chain, beta 2; complement receptor C3 beta-subunit; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor)
- Gene ID
- 3689
- UniProt ID
- B4E0R1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone H52"
See other products for "CD18"
Select a product category from the dropdown menu below to view related products.
Please select product type
Fab Antibody Products
ScFv Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-019 | Human Anti-CD18 Recombinant Antibody (clone H52); Fab Fragment | FC | Human Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for PABZ-019. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: FuncS, Inhib, IP, ELISA
Application: Block, IP, IF, FC
Application: ELISA, IHC, FC, IP, IF, BL
Application: ELISA, IHC, IF, IP, FC, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
