Anti-Human CD98 Recombinant Antibody (IGN523) (CAT#: TAB-147CL)
Recombinant Humanized monoclonal antibody expressed in CHO binding to Human CD98. This is a therapeutic anti-CD98 antibody with multiple mechanisms of action demonstrates anti-tumor efficacy.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17980/117_E9_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17980/117_E9_2_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17980/44152_B_9_5.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17980/44152_B_9_5.jpg
Figure 3 Pancreas
(Pancreatic endocrine cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17980/44152_A_3_3.jpg
(Pancreatic endocrine cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17980/44152_A_3_3.jpg
Figure 4 Kidney
(Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17980/44152_A_8_5.jpg
(Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17980/44152_A_8_5.jpg
Figure 5 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17980/44152_A_4_6.jpg
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17980/44152_A_4_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (hTCEpi, SiHa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168003-SLC3A2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168003-SLC3A2
Specifications
- Derivation
- Humanized
- Type
- Antibody
- Species Reactivity
- Human
- Applications
- ADCC, FuncS
- Related Disease
- Acute myeloid leukemia
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- This antibody has been tested for use in Antibody-dependent Cellular Cytotoxicity Assay and Functional Assay.
Target
- Alternative Names
- CD98; SLC3A2; MDU1; 4T2HC; 4F2; NACAE; SLC7A5; LAT1; E16; D16S469E; MPE16
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD98"
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Chimeric Antibody Products
Human Antibody Products
Mouse Antibody Products
Humanized Antibody Products
IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-381LC | Anti-Human CD98 Recombinant Antibody (cM23) | FC | Chimeric antibody (mouse/human) |
| TAB-381LC-S(P) | Anti-Human CD98 Recombinant Antibody scFv Fragment (cM23) | FC | Chimeric antibody (mouse/human) |
| TAB-381LC-F(E) | Anti-Human CD98 Recombinant Antibody Fab Fragment (cM23) | FC | Chimeric antibody (mouse/human) |
| TAB-396LC-F(E) | Human Anti-CD98 Recombinant Antibody; Fab Fragment (TAB-396LC-F(E)) | FC | Chimeric (Rat/Human) Fab |
| TAB-397LC-F(E) | Human Anti-CD98 Recombinant Antibody; Fab Fragment (TAB-397LC-F(E)) | FC | Chimeric (Rat/Human) Fab |
Customer Reviews and Q&As
Customer Review
Q&As
Specific and Sensitive
The specificity and sensitivity of IGN523 are impressive. It has helped us achieve significant results in detecting CD98 in various assays.
Dependable Supply
We've ordered IGN523 in bulk quantities for large-scale studies, and the supply has always been dependable, with consistent quality in every batch.
No Off-Target Effects
During our experiments, IGN523 showed no off-target effects, maintaining high specificity for CD98 without affecting other proteins.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-147CL, RRID: AB_3111836)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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