Afuco™ Anti-Human CLDN1 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-157CL)
Anti-CLDN1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. Monoclonal antibodies against the HCV entry factor CLDN1 might be used to prevent HCV infection, such as after liver transplantation, and might also restrain virus spread in chronically infected patients.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Liver
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48319/122918_A_8_4.jpg
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48319/122918_A_8_4.jpg
Figure 2 Kidney
(Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48319/122918_A_8_5.jpg
(Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48319/122918_A_8_5.jpg
Figure 3 Testis
(Pachytene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Round or early spermatids
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Sertoli cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48319/122918_A_5_6.jpg
(Pachytene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Round or early spermatids
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Sertoli cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48319/122918_A_5_6.jpg
Figure 4 Skin
(Cells in granular layer
Staining:High
Intensity: Strong
Quantity:>75%
Cells in spinous layer
Staining:High
Intensity: Strong
Quantity:>75%
Hair follicles
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48319/122918_B_9_1.jpg
(Cells in granular layer
Staining:High
Intensity: Strong
Quantity:>75%
Cells in spinous layer
Staining:High
Intensity: Strong
Quantity:>75%
Hair follicles
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48319/122918_B_9_1.jpg
Figure 5 RNA cell line category: Group enriched (EFO-21, HaCaT, hTCEpi, RPTEC TERT1, RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163347-CLDN1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163347-CLDN1
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Hepatitis C viral infection
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CLDN1; claudin 1; CLD1; SEMP1; ILVASC; claudin-1; senescence-associated epithelial membrane protein 1
- Gene ID
- 9076
- UniProt ID
- A5JSJ9
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CLDN1"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-594-VHH | Recombinant Anti-Human CLDN1 VHH Single Domain Antibody | WB, IP, ICC, FC, FA | Llama VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2083z | Mouse Anti-CLDN1 Recombinant Antibody (clone 1B9) | WB, ELISA, IHC | Mouse IgG2a, κ |
| HPAB-0080-LS | Mouse Anti-CLDN1 Recombinant Antibody (HPAB-0080-LS) | WB, FC, IF, IP, Inhib | Mouse IgG |
| HPAB-M0488-YC | Rat Anti-CLDN1 Recombinant Antibody (HPAB-M0488-YC) | FC, Inhib, FuncS | Rat IgG2b, κ |
| HPAB-M0489-YC | Human Anti-CLDN1 Recombinant Antibody (HPAB-M0489-YC) | FC, Inhib, FuncS | Humanized IgG |
| ZG-0154J | Mouse Anti-CLDN1 Recombinant Antibody (ZG-0154J) | IHC-P, IF, WB | Mouse IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-479LC | Anti-Human CLDN1 Recombinant Antibody (3A2) | FC, ELISA, IB, Inhib, IF | |
| TAB-480LC | Anti-Human CLDN1 Recombinant Antibody (2C1) | FC, ELISA, IB, Inhib, IF | |
| TAB-481LC | Anti-Human CLDN1 Recombinant Antibody (5F2) | FC, ELISA, IB, Inhib, IF | |
| TAB-482LC | Anti-Human CLDN1 Recombinant Antibody (7A5) | FC, ELISA, IB, Inhib, IF | |
| TAB-483LC | Mouse Anti-CLDN1 Recombinant Antibody (TAB-483LC) | FC, FuncS, IP, WB | Mouse IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0716 | Hi-Affi™ Rabbit Anti-CLDN1 Recombinant Antibody (clone DS716AB) | IHC-P | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0080-LS-S(P) | Mouse Anti-CLDN1 Recombinant Antibody; scFv Fragment (HPAB-0080-LS-S(P)) | WB, FC, IF, IP, Inhib | Mouse scFv |
| HPAB-M0488-YC-S(P) | Rat Anti-CLDN1 Recombinant Antibody; scFv Fragment (HPAB-M0488-YC-S(P)) | FC, Inhib, FuncS | Rat scFv |
| HPAB-M0489-YC-S(P) | Human Anti-CLDN1 Recombinant Antibody; scFv Fragment (HPAB-M0489-YC-S(P)) | FC, Inhib, FuncS | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0080-LS-F(E) | Mouse Anti-CLDN1 Recombinant Antibody; Fab Fragment (HPAB-0080-LS-F(E)) | WB, FC, IF, IP, Inhib | Mouse Fab |
| HPAB-M0488-YC-F(E) | Rat Anti-CLDN1 Recombinant Antibody; Fab Fragment (HPAB-M0488-YC-F(E)) | FC, Inhib, FuncS | Rat Fab |
| HPAB-M0489-YC-F(E) | Human Anti-CLDN1 Recombinant Antibody; Fab Fragment (HPAB-M0489-YC-F(E)) | FC, Inhib, FuncS | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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