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  • Afuco™ Anti-Human CLEC2D ADCC Recombinant Antibody, ADCC Enhanced

Afuco™ Anti-Human CLEC2D ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-163CL)

Anti-CLEC2D ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is a monoclonal antibody that is capable of specifically binding to lectin-like transcript 1 (LLT1), to polynucleotides encoding such antibodies and to cells that express such antibodies. Antibodies have utility in the treatment of autoimmune diseases and cancer, in which LLT1- and CD161-expressing cells play a role in disease pathogenesis.


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  • Gene Expression
  • Datasheet
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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47584/747_H3_2_selected.jpg
Figure 2 IHC staining of human colon
Figure 2 IHC staining of human colon
(Immunohistochemical staining of human colon shows strong positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17649/ihc_selected.jpg
Figure 3 IF staining of human cell line MCF7
Figure 3 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47584/714_H3_1_blue_red_green.jpg
Figure 4 IF staining of human cell line U-2 OS
Figure 4 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47584/713_H3_2_blue_red_green.jpg
Normal Tissue
Figure 5 Colon
Figure 5 Colon
(Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17649/40429_A_9_3.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in glomeruli
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17649/40429_A_8_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17649/40429_A_4_6.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17649/40429_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Group enriched (Daudi, HDLM-2, Karpas-707, U-698)
Figure 9 RNA cell line category: Group enriched (Daudi, HDLM-2, Karpas-707, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000069493-CLEC2D

Specifications

  • Host Species
  • Chimeric (human/mouse)
  • Derivation
  • Chimeric (human/mouse)
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Autoimmune Diseases

Product Property

  • Purity
  • 90–95% (SDS-PAGE)
  • Storage
  • ≤1 year at -20°C.

Target

  • Alternative Names
  • CLEC2D; C-type lectin domain family 2, member D; CLAX; LLT1; OCIL; C-type lectin domain family 2 member D; LLT-1; C-type lectin related f; lectin-like transcript 1; lectin-like NK cell receptor; osteoclast inhibitory lectin; C-type lectin superfamily 2, member D

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CLEC2D"

Mouse Antibody

CAT Product Name Application Type
TAB-0684CL Mouse Anti-CLEC2D Recombinant Antibody (TAB-0684CL) FC, ELISA Mouse IgG1
TAB-0685CL Mouse Anti-CLEC2D Recombinant Antibody (TAB-0685CL) FC, ELISA Mouse IgG1
TAB-0684CL-S(P) Mouse Anti-CLEC2D Recombinant Antibody; scFv Fragment (TAB-0684CL-S(P)) FC, ELISA Mouse scFv
TAB-0685CL-S(P) Mouse Anti-CLEC2D Recombinant Antibody; scFv Fragment (TAB-0685CL-S(P)) FC, ELISA Mouse scFv
TAB-0684CL-F(E) Mouse Anti-CLEC2D Recombinant Antibody; Fab Fragment (TAB-0684CL-F(E)) FC, ELISA Mouse Fab

Recombinant Antibody

CAT Product Name Application Type
MOB-1109MZ Recombinant Mouse Anti-Mouse CLEC2D Antibody (clone 166C1309) WB Mouse antibody
HPAB-0016-FY Mouse Anti-CLEC2D Recombinant Antibody (HPAB-0016-FY) FC Mouse IgG1
HPAB-650-FY Mouse Anti-CLEC2D Recombinant Antibody (HPAB-650-FY) WB Mouse IgG
VS-0723-WK141 Human Anti-CLEC2D Recombinant Antibody (VS-0723-WK141) FC Chimeric (rabbit/human) IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0720 Hi-Affi™ Rabbit Anti-CLEC2D Recombinant Antibody (clone DS720AB) WB, FC Rabbit IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0016-FY-S(P) Mouse Anti-CLEC2D Recombinant Antibody; scFv Fragment (HPAB-0016-FY-S(P)) FC Mouse scFv
HPAB-650-FY-S(P) Mouse Anti-CLEC2D Recombinant Antibody; scFv Fragment (HPAB-650-FY-S(P)) WB Mouse scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0016-FY-F(E) Mouse Anti-CLEC2D Recombinant Antibody; Fab Fragment (HPAB-0016-FY-F(E)) FC Mouse Fab
HPAB-650-FY-F(E) Mouse Anti-CLEC2D Recombinant Antibody; Fab Fragment (HPAB-650-FY-F(E)) WB Mouse Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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