Anti-CSF3R ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is a fully human antibody that binds to the G-CSFR, and neutralises the activity of G-CSF in various in vitro assays. It inhibits the G-CSF mediated expression of CXCR1 and CXCR2 on neutrophils which correlates with reduced migratory potential to various chemo-attractants. In vivo NHP studies demonstrate that administration of It is well tolerated and does not result in neutropenia supporting the development of this antibody for indications where neutrophils contribute to the disease pathogenesis.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-722-sdAb | Recombinant Anti-Human CSF3R VHH Single Domain Antibody | IHC, ICC, FC, FA, FUNC | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1808z | Mouse Anti-CSF3R Recombinant Antibody (clone 28F2) | WB, ELISA, FC, IHC | Mouse IgG1 |
MOB-0140CT | Recombinant Mouse anti-Human CSF3R Monoclonal antibody (MNN886) | FC | |
HPAB-0081-YJ | Mouse Anti-CSF3R Recombinant Antibody (clone LMM-741) | FC, IP, WB | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-548CQ | Rat Anti-Csf3r Recombinant Antibody (VMC178) | Neut | Rat IgG2b |
NEUT-549CQ | Rat Anti-Csf3r Recombinant Antibody (clone CBL638) | Neut | Rat IgG2b |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0829 | Hi-Affi™ Rabbit Anti-CSF3R Recombinant Antibody (clone DS829AB) | WB, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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