Mouse Anti-Dabigatran Recombinant Antibody (clone 15C9); Fab Fragment

CAT#: PFBZ-167

Recombinant Mouse Antibody (15C9) Fab Fragment is specific to Dabigatran, expressed in Chinese Hamster Ovary cells (CHO). The dabigatran binding site of the aDabi-Fab is located in a concave region at the interface of the variable domains.

Specifications

  • Immunogen
  • Dabigatran etexilate
  • Host Species
  • Mouse
  • Type
  • Mouse Fab
  • Clone
  • 15C9
  • Applications
  • ELISA, Neut

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Dabigatran; Pradaxa; Prazaxa; Dabigatran etexilate
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Breast cancer biomarkers at key points during disease progression
Precise Fab Fragment Binding
This recombinant mouse Fab fragment (clone 15C9) was exactly what we needed for our structural interface studies. It binds specifically to Dabigatran in our ELISA setup. The fact that it is a Fab fragment rather than a whole IgG reduced non-specific interactions in our assay.
Breast cancer biomarkers at key points during disease progression
Great For Neutralization Assays
We tested this antibody in neutralization assays involving Dabigatran etexilate derivatives. It performed well, confirming the binding site is located in the variable domains as described. The product arrived in good condition and the purity via HPLC analysis was as promised.

Q&As

  1. What host species is this antibody derived from?

    A: This antibody fragment is derived from a Mouse host. It is a recombinant mouse antibody (clone 15C9) that has been engineered and expressed in a mammalian system (CHO cells) to ensure consistent performance in applications like ELISA and Neutralization.

  2. Is this a full-length IgG molecule?

    A: No, this product is a recombinant Fab fragment, not a full-length IgG. It is expressed in Chinese Hamster Ovary (CHO) cells. The Fab fragment contains the variable domains where the dabigatran binding site is located, specifically in a concave region at the interface.

View the frequently asked questions answered by Creative Biolabs Support.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# PFBZ-167, RRID: AB_3714233)

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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