Anti-Human EPHA4 Recombinant Antibody (65)
CAT#: TAB-386MZ
Recombinant monoclonal antibody to EphA4. Mab 65 is a human monoclonal antibody intended for the prophylaxis and treatment of related disease. This anti-EphA4 human antibody can induce ADCC effects in tumor cells that overexpresse EphA4, while no effect against cells with EphA4 low-expression.
Published Data
Gene Expression
Cyt
Figure 1 depicts the results of an ADCC assay using Herceptin and anti-EphA4 human antibody 65 and 336 against EphA4-over- and -low-expressing pancreatic cancer cell line, MIAPaca-2 and PK-45P.
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Normal Tissue
Figure 1 Cerebral cortex
Neuropil
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28368/71560_B_7_5.jpg
Normal Tissue
Figure 2 Cerebellum
Molecular layer - neuropil
Staining:Medium
Intensity: Moderate
Molecular layer cells - cytoplasm/membrane
Staining:High
Intensity: Strong
Synaptic glomeruli - capsule
Staining:Medium
Intensity: Moderate
Synaptic glomeruli - core
Staining:Medium
Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28368/71560_B_8_8.jpg
Normal Tissue
Figure 3 Colon
Enterocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28368/71560_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Proximal tubules (cell body)
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28368/71560_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Elongated or late spermatids
Staining:Medium
Intensity: Moderate
Quantity:>75%
Sertoli cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28368/71560_A_5_6.jpg
Normal Tissue
Figure 6 RNA cell line category: Cell line enhanced (AF22, ASC diff, CACO-2, U-2197)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000116106-EPHA4
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Specifications
- Host Species
- Human
- Derivation
- Phage library
- Type
- Human antibody
- Specificity
- Human
- Clone
- 65
- Applications
- Cyt
- Related Disease
- Pancreatic cancer
Applications
- Application Notes
- This antibody has been reported for use in Cytotoxicity.
Target
- Alternative Names
- EPHA4; EPH receptor A4; SEK; HEK8; TYRO1; ephrin type-A receptor 4; EK8; EPH-like kinase 8; TYRO1 protein tyrosine kinase; tyrosine-protein kinase TYRO1; tyrosine-protein kinase receptor SEK; receptor protein-tyrosine kinase HEK8
- Gene ID
- 2043
- UniProt ID
- A0A024R452
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 65"
- CAT
- Product Name
See other products for "EPHA4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-387MZ | Anti-Human EPHA4 Recombinant Antibody (336) | Cyt | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-388MZ | Anti-Human EPHA4 Recombinant Antibody (EphA4-44/EA44) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-386MZ-S(P) | Anti-Human EPHA4 Recombinant Antibody scFv Fragment (65) | FC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-387MZ-S(P) | Anti-Human EPHA4 Recombinant Antibody scFv Fragment (336) | FC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-388MZ-S(P) | Anti-Human EPHA4 Recombinant Antibody scFv Fragment (EphA4-44/EA44) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-386MZ-F(E) | Anti-Human EPHA4 Recombinant Antibody Fab Fragment (65) | FC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-387MZ-F(E) | Anti-Human EPHA4 Recombinant Antibody Fab Fragment (336) | FC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-388MZ-F(E) | Anti-Human EPHA4 Recombinant Antibody Fab Fragment (EphA4-44/EA44) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0652CT | Recombinant Mouse anti-Human EPHA4 Monoclonal antibody (EML064) | WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0004-DJB | Human Anti-EPHA4 Recombinant Antibody (HPAB-0004-DJB) | ELISA, Block | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0005-DJB | Human Anti-EPHA4 Recombinant Antibody (HPAB-0005-DJB) | ELISA, Block | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0006-DJB | Human Anti-EPHA4 Recombinant Antibody (HPAB-0006-DJB) | ELISA, Block | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0004-DJB-S(P) | Human Anti-EPHA4 Recombinant Antibody; scFv Fragment (HPAB-0004-DJB-S(P)) | ELISA, Block | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0005-DJB-S(P) | Human Anti-EPHA4 Recombinant Antibody; scFv Fragment (HPAB-0005-DJB-S(P)) | ELISA, Block | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0006-DJB-S(P) | Human Anti-EPHA4 Recombinant Antibody scFv Fragment (HPAB-0006-DJB-S(P)) | ELISA, Block | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0004-DJB-F(E) | Human Anti-EPHA4 Recombinant Antibody; Fab Fragment (HPAB-0004-DJB-F(E)) | ELISA, Block | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0005-DJB-F(E) | Human Anti-EPHA4 Recombinant Antibody; Fab Fragment (HPAB-0005-DJB-F(E)) | ELISA, Block | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0006-DJB-F(E) | Human Anti-EPHA4 Recombinant Antibody Fab Fragment (HPAB-0006-DJB-F(E)) | ELISA, Block | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0156-FY | Human Anti-EPHA4 Recombinant Antibody (clone SC4.15) | Inhib | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0156-FY-S(P) | Human Anti-EPHA4 Recombinant Antibody (clone SC4.15); scFv Fragment | Inhib | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0156-FY-F(E) | Human Anti-EPHA4 Recombinant Antibody (clone SC4.15); Fab Fragment | Inhib | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY80 | Human Anti-EPHA4 (clone 10C12) scFv-Fc Chimera | FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC8 | Recombinant Anti-EPHA4 Vesicular Antibody, EV Displayed (VS-0425-YC8) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2311 | Anti-Mouse EPHA4 Immunohistochemistry Kit | IHC |
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