Anti-Human EPHA4 Recombinant Antibody (65) (CAT#: TAB-386MZ)

Recombinant monoclonal antibody to EphA4. Mab 65 is a human monoclonal antibody intended for the prophylaxis and treatment of related disease. This anti-EphA4 human antibody can induce ADCC effects in tumor cells that overexpresse EphA4, while no effect against cells with EphA4 low-expression.


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Cyt

Figure 1 depicts the results of an ADCC assay using Herceptin and anti-EphA4 human antibody 65 and 336 against EphA4-over- and -low-expressing pancreatic cancer cell line, MIAPaca-2 and PK-45P.

Figure 1 depicts the results of an ADCC assay using Herceptin and anti-EphA4 human antibody 65 and 336 against EphA4-over- and -low-expressing pancreatic cancer cell line, MIAPaca-2 and PK-45P.


Specifications

  • Host Species
  • Human
  • Derivation
  • Phage library
  • Type
  • Human antibody
  • Specificity
  • Human
  • Clone
  • 65
  • Applications
  • Cyt
  • Related Disease
  • Pancreatic cancer

Applications

  • Application Notes
  • This antibody has been reported for use in Cytotoxicity.

Target

  • Alternative Names
  • EPHA4; EPH receptor A4; SEK; HEK8; TYRO1; ephrin type-A receptor 4; EK8; EPH-like kinase 8; TYRO1 protein tyrosine kinase; tyrosine-protein kinase TYRO1; tyrosine-protein kinase receptor SEK; receptor protein-tyrosine kinase HEK8

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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