Afuco™ Anti-Human ERG ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-235CL)
Anti-ERG ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The monoclonal antibodies that bind to ERG can be used to treat malignancies associated with overexpression of ERG or an ERG fusion event, such as prostate cancer, Ewing's sarcoma, acute myeloid leukemia, acute T-lymphoblastic leukemia, endothelial cancer, and colon cancer.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/if_selected.jpg
Figure 2 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows moderate nuclear positivity in cells in tubules and cells in glomeruli.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46598/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows moderate nuclear positivity in cells in tubules and cells in glomeruli.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46598/ihc_selected.jpg
Figure 3 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong positivity in cells of red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/ihc_selected.jpg
(Immunohistochemical staining of human spleen shows strong positivity in cells of red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/ihc_selected.jpg
Figure 4 Cerebral cortex
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_B_9_5.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_B_9_5.jpg
Figure 5 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_A_9_3.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_A_9_3.jpg
Figure 6 Liver
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_A_8_4.jpg
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_A_8_4.jpg
Figure 7 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_A_8_5.jpg
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_A_8_5.jpg
Figure 8 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_A_7_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_A_7_8.jpg
Figure 9 RNA cell line category: Group enriched (HUVEC TERT2, MOLT-4, REH, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157554-ERG
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157554-ERG
Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% (SDS-PAGE)
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- ERG; v-ets avian erythroblastosis virus E26 oncogene homolog; p55; erg-3; transcriptional regulator ERG; ets-related; TMPRSS2/ERG fusion; v-ets erythroblastosis virus E26 oncogene like; v-ets erythroblastosis virus E26 oncogene homolog; v-ets avian erythroblastosis virus E26 oncogene related; transcriptional regulator ERG (transforming protein ERG)
- Gene ID
- 2078
- UniProt ID
- B4DN83
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-332 | Recombinant Anti-human ERG Antibody | WB, Neut, FuncS | IgG |
| MHH-332 | Recombinant Human Anti-human ERG Antibody | ELISA, WB, Neut, FuncS | IgG |
| MRO-0542-CN | Rabbit Anti-ERG Recombinant Antibody (clone CBACN-214) | WB, IF, IHC, ChIP | Rabbit IgG |
| MRO-1843-CN | Rabbit Anti-ERG Polyclonal Antibody (MRO-1843-CN) | WB, IF, IHC | Rabbit IgG |
| VS3-CJ588 | Rabbit Anti-ERG Recombinant Antibody (VS3-CJ588) | WB, ICC, IF, IHC, ChIP | Rabbit IgG |
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