Afuco™ Anti-Human ERG ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-235CL
Anti-ERG ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The monoclonal antibodies that bind to ERG can be used to treat malignancies associated with overexpression of ERG or an ERG fusion event, such as prostate cancer, Ewing's sarcoma, acute myeloid leukemia, acute T-lymphoblastic leukemia, endothelial cancer, and colon cancer.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human kidney
Immunohistochemical staining of human kidney shows moderate nuclear positivity in cells in tubules and cells in glomeruli.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46598/ihc_selected.jpg
Normal Tissue
Figure 3 IHC staining of human spleen
Immunohistochemical staining of human spleen shows strong positivity in cells of red pulp.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_A_9_3.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_A_8_4.jpg
Normal Tissue
Figure 7 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_A_8_5.jpg
Normal Tissue
Figure 8 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18377/40670_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Group enriched (HUVEC TERT2, MOLT-4, REH, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157554-ERG
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Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% (SDS-PAGE)
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- ERG; v-ets avian erythroblastosis virus E26 oncogene homolog; p55; erg-3; transcriptional regulator ERG; ets-related; TMPRSS2/ERG fusion; v-ets erythroblastosis virus E26 oncogene like; v-ets erythroblastosis virus E26 oncogene homolog; v-ets avian erythroblastosis virus E26 oncogene related; transcriptional regulator ERG (transforming protein ERG)
- Gene ID
- 2078
- UniProt ID
- B4DN83
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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|---|---|---|---|
| MOB-332 | Recombinant Anti-human ERG Antibody | WB, Neut, FuncS | IgG |
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| MOB-332-F(E) | Recombinant Anti-human ERG Antibody Fab Fragment | RIA, ELISA, FuncS | Fab |
| CAT | Product Name | Application | Type |
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| MOB-332-S(P) | Recombinant Anti-human ERG Antibody scFv Fragment | WB, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
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| MHH-332 | Recombinant Human Anti-human ERG Antibody | ELISA, WB, Neut, FuncS | IgG |
| CAT | Product Name | Application | Type |
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| MHH-332-F(E) | Recombinant Human Anti-human ERG Antibody Fab Fragment | WB, IP, FuncS | Fab |
| CAT | Product Name | Application | Type |
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| MHH-332-S(P) | Recombinant Human Anti-human ERG Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-012WM | Mouse Anti-ERG Recombinant Antibody (TAB-012WM) | WB, ELISA, IP, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-012WM-S(P) | Mouse Anti-ERG Recombinant Antibody; scFv Fragment (TAB-012WM-S(P)) | WB, ELISA, IP, IF | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-012WM-F(E) | Mouse Anti-ERG Recombinant Antibody; Fab Fragment (TAB-012WM-F(E)) | WB, ELISA, IP, IF | Mouse Fab |
| CAT | Product Name | Application | Type |
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| MOR-1186 | Hi-Affi™ Rabbit Anti-ERG Recombinant Antibody (clone DS1186AB) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| MRO-0542-CN | Rabbit Anti-ERG Recombinant Antibody (clone CBACN-214) | WB, IF, IHC, ChIP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1843-CN | Rabbit Anti-ERG Polyclonal Antibody (MRO-1843-CN) | WB, IF, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-CJ588 | Rabbit Anti-ERG Recombinant Antibody (VS3-CJ588) | WB, ICC, IF, IHC, ChIP | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| VS-0525-XY2347 | Anti-ERG Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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| VS-0525-XY2348 | Anti-Mouse ERG Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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| VS-0525-XY2349 | Anti-Rat ERG Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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