Afuco™ Anti-Human FCAR ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-251CL)
Anti-FCAR ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The human monoclonal antibodies which bind specifically to Fc alpha receptor (CD89) are useful for targeting human effector cells (such as macrophages) against a target cell (such as a cancer cell, an infectious agent, etc. ).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/if_selected.jpg
Figure 2 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in reaction center cells and lymphoid cells outside reaction centra.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/ihc_selected.jpg
(Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in reaction center cells and lymphoid cells outside reaction centra.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/ihc_selected.jpg
Figure 3 Bone marrow
(Hematopoietic cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/32713_B_4_4.jpg
(Hematopoietic cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/32713_B_4_4.jpg
Figure 4 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/32713_A_9_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/32713_A_9_8.jpg
Figure 5 RNA cell line category: Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186431-FCAR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186431-FCAR
Figure 5 RNA cell line category: Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186431-FCAR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186431-FCAR
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% by HPLC
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor
- Gene ID
- 2204
- UniProt ID
- P24071
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1200z | Mouse Anti-FCAR Recombinant Antibody (clone 44C11) | WB, ELISA, FC, IP | Mouse IgG1 |
| MOB-0522CT | Recombinant Mouse anti-Human FCAR Monoclonal antibody (NJQ8d) | FC, Inhib | |
| FN-142CQ | Human Anti-FCAR Recombinant Antibody (clone CBL-1311) | FuncS, Block | Human IgG1 |
| HPAB-1202WJ | Human Anti-FCAR Recombinant Antibody (clone 14A8) | ELISA, FC | Human IgG |
| HPAB-1203WJ | Human Anti-FCAR Recombinant Antibody (clone 8D2) | ELISA, FC | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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