Afuco™ Anti-Human FCAR ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-251CL)
Anti-FCAR ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The human monoclonal antibodies which bind specifically to Fc alpha receptor (CD89) are useful for targeting human effector cells (such as macrophages) against a target cell (such as a cancer cell, an infectious agent, etc. ).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/if_selected.jpg
Figure 2 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in reaction center cells and lymphoid cells outside reaction centra.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/ihc_selected.jpg
(Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in reaction center cells and lymphoid cells outside reaction centra.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/ihc_selected.jpg
Figure 3 Bone marrow
(Hematopoietic cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/32713_B_4_4.jpg
(Hematopoietic cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/32713_B_4_4.jpg
Figure 4 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/32713_A_9_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14050/32713_A_9_8.jpg
Figure 5 RNA cell line category: Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186431-FCAR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186431-FCAR
Figure 5 RNA cell line category: Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186431-FCAR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186431-FCAR
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% by HPLC
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor
- Gene ID
- 2204
- UniProt ID
- P24071
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1200z | Mouse Anti-FCAR Recombinant Antibody (clone 44C11) | WB, ELISA, FC, IP | Mouse IgG1 |
| MOB-0522CT | Recombinant Mouse anti-Human FCAR Monoclonal antibody (NJQ8d) | FC, Inhib | |
| FN-142CQ | Human Anti-FCAR Recombinant Antibody (clone CBL-1311) | FuncS, Block | Human IgG1 |
| HPAB-1202WJ | Human Anti-FCAR Recombinant Antibody (clone 14A8) | ELISA, FC | Human IgG |
| HPAB-1203WJ | Human Anti-FCAR Recombinant Antibody (clone 8D2) | ELISA, FC | Human IgG |
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