Afuco™ Anti-Human GAP43 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-286CL
Anti-GAP43 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies to the growth-associated protein, GAP-43, introduced intracellularly using a lipid carrier, blocked the differentiation induced by dbcAMP. Antibodies to GAP43, at a low concentration, blocked neurite out-growth induced by serum withdrawal when cells were grown on a relatively unadhesive substrate.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13392/1510_B4_2_selected.jpg
Normal Tissue
Figure 2 Colon
Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15600/35117_A_8_3.jpg
Normal Tissue
Figure 3 High expression in cerebral cortex
Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15600/35117_B_9_5.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (AF22, NTERA-2, SCLC-21H, SH-SY5Y, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172020-GAP43
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Specifications
- Host Species
- Chimeric human/mouse
- Type
- ADCC enhanced antibody
- Species Reactivity
- Mouse
- Related Disease
- Nervous System Diseases
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- GAP43; growth associated protein 43; B-50; PP46; neuromodulin; protein F1; neural phosphoprotein B-50; growth-associated protein 43; axonal membrane protein GAP-43; calmodulin-binding protein P-57; nerve growth-related peptide GAP43; neuron growth-associated protein 43
- Gene ID
- 2596
- UniProt ID
- P17677
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "GAP43"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1629z | Mouse Anti-GAP43 Recombinant Antibody (clone 29G1) | WB, ICC, IF, IHC | Mouse IgG1 |
| MRO-0629-CN | Rabbit Anti-GAP43 Recombinant Antibody (clone CBACN-234) | WB, IF, IHC, IP, FC | Rabbit IgG |
| VS3-WK1360 | Mouse Anti-GAP43 Recombinant Antibody (VS3-WK1360) | WB, IF, IHC-P | Mouse IgG |
| VS3-WK1428 | Mouse Anti-GAP43 Antibody (clone Mix-mA) | WB | Mouse IgG1 |
| VS4-WK188 | Mouse Anti-GAP43 Recombinant Antibody (VS4-WK188) | ELISA, WB, IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0698MZ | Chicken Anti-Gap43 Polyclonal IgY | ICC, IF, IHC, WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1397 | Hi-Affi™ Rabbit Anti-GAP43 Recombinant Antibody (clone DS1397AB) | WB, IP, ICC, FC, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC684 | AbPlus™ Anti-GAP43 Magnetic Beads (VS-0724-YC684) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2725 | Anti-GAP43 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2726 | Anti-Mouse GAP43 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2727 | Anti-Rat GAP43 Immunohistochemistry Kit | IHC |
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